could compromise their ability to control pathogenic cells, and activation of NOD APC could restore this defect, thereby preventing disease. compared to APC from untreated NOD mice.These data suggest that regulatory T cell function and ability to control pathogenic cells can be enhanced in NOD mice by activating NOD APC
International audienceRegulatory T cell (Treg) insufficiency licenses the destruction of insulin-pro...
OBJECTIVE—Autoimmune diabetes in the nonobese diabetic (NOD) mouse model results from a breakdown of...
International audienceRegulatory T cell (Treg) insufficiency licenses the destruction of insulin-pro...
Various defects in antigen-presenting cells (APCs) and T-cells, including regulatory cells, have bee...
Although T lymphocytes are the ultimate effectors of pancreatic beta cell destruction in autoimmune ...
Autoimmunity in the NOD mouse is a paradigm of dysregulated T cell tolerance where anti-islet T cell...
BACKGROUND: Disturbed peripheral negative regulation might contribute to evolution of autoimmune ins...
The many commonalities between the development of autoimmune diabetes in the NOD mouse and its devel...
The many commonalities between the development of autoimmune diabetes in the NOD mouse and its devel...
Non-obese diabetic (NOD) mice are an excellent model of T-cell mediated autoimmune insulin-dependent...
Genetically-controlled defects in the development and function of antigen presenting cells may expla...
Disturbed peripheral negative regulation might contribute to evolution of autoimmune insulitis in ty...
Thymic and peripheral T-cells from NOD mice display a proliferative unresponsiveness on stimulation ...
Thymic and peripheral T-cells from NOD mice display a proliferative unresponsiveness on stimulation ...
Disturbed peripheral negative regulation might contribute to evolution of autoimmune insulitis in ty...
International audienceRegulatory T cell (Treg) insufficiency licenses the destruction of insulin-pro...
OBJECTIVE—Autoimmune diabetes in the nonobese diabetic (NOD) mouse model results from a breakdown of...
International audienceRegulatory T cell (Treg) insufficiency licenses the destruction of insulin-pro...
Various defects in antigen-presenting cells (APCs) and T-cells, including regulatory cells, have bee...
Although T lymphocytes are the ultimate effectors of pancreatic beta cell destruction in autoimmune ...
Autoimmunity in the NOD mouse is a paradigm of dysregulated T cell tolerance where anti-islet T cell...
BACKGROUND: Disturbed peripheral negative regulation might contribute to evolution of autoimmune ins...
The many commonalities between the development of autoimmune diabetes in the NOD mouse and its devel...
The many commonalities between the development of autoimmune diabetes in the NOD mouse and its devel...
Non-obese diabetic (NOD) mice are an excellent model of T-cell mediated autoimmune insulin-dependent...
Genetically-controlled defects in the development and function of antigen presenting cells may expla...
Disturbed peripheral negative regulation might contribute to evolution of autoimmune insulitis in ty...
Thymic and peripheral T-cells from NOD mice display a proliferative unresponsiveness on stimulation ...
Thymic and peripheral T-cells from NOD mice display a proliferative unresponsiveness on stimulation ...
Disturbed peripheral negative regulation might contribute to evolution of autoimmune insulitis in ty...
International audienceRegulatory T cell (Treg) insufficiency licenses the destruction of insulin-pro...
OBJECTIVE—Autoimmune diabetes in the nonobese diabetic (NOD) mouse model results from a breakdown of...
International audienceRegulatory T cell (Treg) insufficiency licenses the destruction of insulin-pro...