Fas-Mediated Apoptosis Regulates the Composition of Peripheral αβ T Cell Repertoire by Constitutively Purging Out Double Negative T Cells

TWO WAY STREET By

Ahmet Zeytun
Ahmet Zeytun
Dr. Prakash
S. Nagarkatti

January 1999

We investigated the role of Fas ligand in the development of anti-tumor immunity. The LSA tumor spec...

Elimination of Antigen-Presenting Cells and Autoreactive T Cells by Fas Contributes to Prevention of Autoimmunity

Stranges, Peter B.
Watson, Jessica
Cooper, Cristie J.
Choisy-Rossi, Caroline-Morgane
Stonebraker, Austin C.
Beighton, Ryan A.
Hartig, Heather
Sundberg, John P.
Servick, Stein
Kaufmann, Gunnar
Fink, Pamela J.
Chervonsky, Alexander V.

May 2007

SummaryFas (also known as Apo-1 and CD95) receptor has been suggested to control T cell expansion by...

Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunity.

Stranges, P B
Watson, J
Cooper, C J
Choisy, Rossi C
Stonebraker, A C
Beighton, R A
Hartig, H
Sundberg, J P
Servick, S
Kaufmann, G
Fink, P J
Chervonsky, A V

January 2007

Fas (also known as Apo-1 and CD95) receptor has been suggested to control T cell expansion by trigge...

Fas-Mediated Apoptosis Regulates the Composition of Peripheral αβ T Cell Repertoire by Constitutively Purging Out Double Negative T Cells

Mohamood Abdiaziz S.
Bargatze Dylan
Xiao Zuoxiang
Jie Chunfa
Yagita Hideo
Ruben Dawn
Watson Julie
Chakravarti Shukti
Schneck Jonathan P.
Hamad Abdel Rahim A.

October 2008

DN T cells.DN T cell lymphoproliferation.The Fas pathway plays a critical role in regulating the tis...

Fas-mediated apoptosis regulates the composition of peripheral alphabeta T cell repertoire by constitutively purging out double negative T cells.

Abdiaziz S Mohamood
Dylan Bargatze
Zuoxiang Xiao
Chunfa Jie
Hideo Yagita
Dawn Ruben
Julie Watson
Shukti Chakravarti
Jonathan P Schneck
Abdel Rahim A Hamad

BACKGROUND: The Fas pathway is a major regulator of T cell homeostasis, however, the T cell populati...

Apoptosis and the maintenance of homeostasis in the immune system

Osborne, Barbara A.

January 1996

The regulation of cell proliferation and the selection against autoreactive cells in the lymphoid sy...

Involvement of the Fas (CD95) system in peripheral cell death and lymphoid organ development

Laouar, Yasmina
Sarukhan, Adelaida
Pasqualetto, Valerie
Garcia, Corinne
Ezine, Sophie

March 1998

International audienceFas‐mediated apoptosis is a form of cell death that operates through a Fas‐Fas...

Fas Modulation of Apoptosis during Negative Selection of Thymocytes

Castro, Januario E.
Listman, James A.
Jacobson, Bruce A.
Wang, Yunsheng
Lopez, Peter A.
Ju, Sherte
Finn, Patricia W.
Perkins, David L.

December 1996

AbstractA major mechanism maintaining immune tolerance is the deletion of potentially autoreactive t...

Regulation of Fas-deficient Lymphoproliferative Double Negative T Cells by Interferon Gamma and the Fc Receptor Gamma Chain

Juvet, Stephen

March 2013

The Fas pathway is critical for the maintenance of normal T cell homeostasis. Humans and mice with ...

The Many Roles of FAS Receptor Signaling in the Immune System

Strasser, Andreas
Jost, Philipp J.
Nagata, Shigekazu

February 2009

SummaryFAS belongs to the subgroup of the tumor necrosis factor receptor (TNF-R) family that contain...

On How Fas Apoptosis-Independent Pathways Drive T Cell Hyperproliferation and Lymphadenopathy in lpr Mice

Balomenos, Dimitrios
Shokri, Rahman
Daszkiewicz, Lidia
Vázquez-Mateo, Cristina
Martínez-A, Carlos

March 2017

FcRγ promotes T cell apoptosis in Fas-deficient mice.

Juvet, SC
Thomson, CW
Kim, EY
Joe, B
Adeyi, O
Zhang, L

May 2013

Deficiency of Fas or its ligand leads to lymphocyte accumulation, lymphadenopathy, splenomegaly, and...

Antigen-Dependent Release of IFN-γ by Cytotoxic T Cells Up- Regulates Fas on Target Cells and Facilitates Exocytosis- Independent Specific Target Cell Lysis

Müllbacher, A.
Lobigs, M.
Hla, R.
Tran, T.
Stehle, T.
Simon, M.

July 2002

Effector cytolytic T (Tc) lymphocytes, deficient in the exocytosis-mediated pathway of target cell l...

Antigen-dependent release of IFN-gamma by cytotoxic T cells up-regulates Fas on target cells and facilitates exocytosis-independent specific target cell lysis

Mullbacher, Arno
Lobigs, Mario
Tha Hla, Ron
Tran, Thao (Thomas)
Stehle, Thomas
Simon, Markus M

December 2015

Effector cytolytic T (Tc) lymphocytes, deficient in the exocytosis-mediated pathway of target cell l...

Apoptosis of tumor-infiltrating T lymphocytes: a new immune checkpoint mechanism

Zhu, J
Petit, P
Van Den Eynde, B

January 2018

Immunotherapy based on checkpoint inhibitors is providing substantial clinical benefit, but only to ...

TWO WAY STREET By

Ahmet Zeytun
Ahmet Zeytun
Dr. Prakash
S. Nagarkatti

January 1999

We investigated the role of Fas ligand in the development of anti-tumor immunity. The LSA tumor spec...

Elimination of Antigen-Presenting Cells and Autoreactive T Cells by Fas Contributes to Prevention of Autoimmunity

Stranges, Peter B.
Watson, Jessica
Cooper, Cristie J.
Choisy-Rossi, Caroline-Morgane
Stonebraker, Austin C.
Beighton, Ryan A.
Hartig, Heather
Sundberg, John P.
Servick, Stein
Kaufmann, Gunnar
Fink, Pamela J.
Chervonsky, Alexander V.

May 2007

SummaryFas (also known as Apo-1 and CD95) receptor has been suggested to control T cell expansion by...

Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunity.

Stranges, P B
Watson, J
Cooper, C J
Choisy, Rossi C
Stonebraker, A C
Beighton, R A
Hartig, H
Sundberg, J P
Servick, S
Kaufmann, G
Fink, P J
Chervonsky, A V

January 2007

Fas (also known as Apo-1 and CD95) receptor has been suggested to control T cell expansion by trigge...

Fas-Mediated Apoptosis Regulates the Composition of Peripheral αβ T Cell Repertoire by Constitutively Purging Out Double Negative T Cells

Mohamood Abdiaziz S.
Bargatze Dylan
Xiao Zuoxiang
Jie Chunfa
Yagita Hideo
Ruben Dawn
Watson Julie
Chakravarti Shukti
Schneck Jonathan P.
Hamad Abdel Rahim A.

October 2008

DN T cells.DN T cell lymphoproliferation.The Fas pathway plays a critical role in regulating the tis...

Fas-mediated apoptosis regulates the composition of peripheral alphabeta T cell repertoire by constitutively purging out double negative T cells.

Abdiaziz S Mohamood
Dylan Bargatze
Zuoxiang Xiao
Chunfa Jie
Hideo Yagita
Dawn Ruben
Julie Watson
Shukti Chakravarti
Jonathan P Schneck
Abdel Rahim A Hamad

BACKGROUND: The Fas pathway is a major regulator of T cell homeostasis, however, the T cell populati...

Apoptosis and the maintenance of homeostasis in the immune system

Osborne, Barbara A.

January 1996

The regulation of cell proliferation and the selection against autoreactive cells in the lymphoid sy...

Involvement of the Fas (CD95) system in peripheral cell death and lymphoid organ development

Laouar, Yasmina
Sarukhan, Adelaida
Pasqualetto, Valerie
Garcia, Corinne
Ezine, Sophie

March 1998

International audienceFas‐mediated apoptosis is a form of cell death that operates through a Fas‐Fas...

Fas Modulation of Apoptosis during Negative Selection of Thymocytes

Castro, Januario E.
Listman, James A.
Jacobson, Bruce A.
Wang, Yunsheng
Lopez, Peter A.
Ju, Sherte
Finn, Patricia W.
Perkins, David L.

December 1996

AbstractA major mechanism maintaining immune tolerance is the deletion of potentially autoreactive t...

Regulation of Fas-deficient Lymphoproliferative Double Negative T Cells by Interferon Gamma and the Fc Receptor Gamma Chain

Juvet, Stephen

March 2013

The Fas pathway is critical for the maintenance of normal T cell homeostasis. Humans and mice with ...

The Many Roles of FAS Receptor Signaling in the Immune System

Strasser, Andreas
Jost, Philipp J.
Nagata, Shigekazu

February 2009

SummaryFAS belongs to the subgroup of the tumor necrosis factor receptor (TNF-R) family that contain...

On How Fas Apoptosis-Independent Pathways Drive T Cell Hyperproliferation and Lymphadenopathy in lpr Mice

Balomenos, Dimitrios
Shokri, Rahman
Daszkiewicz, Lidia
Vázquez-Mateo, Cristina
Martínez-A, Carlos

March 2017

FcRγ promotes T cell apoptosis in Fas-deficient mice.

Juvet, SC
Thomson, CW
Kim, EY
Joe, B
Adeyi, O
Zhang, L

May 2013

Deficiency of Fas or its ligand leads to lymphocyte accumulation, lymphadenopathy, splenomegaly, and...

Antigen-Dependent Release of IFN-γ by Cytotoxic T Cells Up- Regulates Fas on Target Cells and Facilitates Exocytosis- Independent Specific Target Cell Lysis

Müllbacher, A.
Lobigs, M.
Hla, R.
Tran, T.
Stehle, T.
Simon, M.

July 2002

Effector cytolytic T (Tc) lymphocytes, deficient in the exocytosis-mediated pathway of target cell l...

Antigen-dependent release of IFN-gamma by cytotoxic T cells up-regulates Fas on target cells and facilitates exocytosis-independent specific target cell lysis

Mullbacher, Arno
Lobigs, Mario
Tha Hla, Ron
Tran, Thao (Thomas)
Stehle, Thomas
Simon, Markus M

December 2015

Effector cytolytic T (Tc) lymphocytes, deficient in the exocytosis-mediated pathway of target cell l...

Apoptosis of tumor-infiltrating T lymphocytes: a new immune checkpoint mechanism

Zhu, J
Petit, P
Van Den Eynde, B

January 2018

Immunotherapy based on checkpoint inhibitors is providing substantial clinical benefit, but only to ...

TWO WAY STREET By

Ahmet Zeytun
Ahmet Zeytun
Dr. Prakash
S. Nagarkatti

January 1999

We investigated the role of Fas ligand in the development of anti-tumor immunity. The LSA tumor spec...

Elimination of Antigen-Presenting Cells and Autoreactive T Cells by Fas Contributes to Prevention of Autoimmunity

Stranges, Peter B.
Watson, Jessica
Cooper, Cristie J.
Choisy-Rossi, Caroline-Morgane
Stonebraker, Austin C.
Beighton, Ryan A.
Hartig, Heather
Sundberg, John P.
Servick, Stein
Kaufmann, Gunnar
Fink, Pamela J.
Chervonsky, Alexander V.

May 2007

SummaryFas (also known as Apo-1 and CD95) receptor has been suggested to control T cell expansion by...

Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunity.

Stranges, P B
Watson, J
Cooper, C J
Choisy, Rossi C
Stonebraker, A C
Beighton, R A
Hartig, H
Sundberg, J P
Servick, S
Kaufmann, G
Fink, P J
Chervonsky, A V

January 2007

Fas (also known as Apo-1 and CD95) receptor has been suggested to control T cell expansion by trigge...

Fas-Mediated Apoptosis Regulates the Composition of Peripheral αβ T Cell Repertoire by Constitutively Purging Out Double Negative T Cells

Abstract

Extracted data

Fas-Mediated Apoptosis Regulates the Composition of Peripheral αβ T Cell Repertoire by Constitutively Purging Out Double Negative T Cells

Abstract

Extracted data

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