Computed Tomography Structural Lung Changes in Discordant Airflow Limitation
- Hoesein Firdaus A. A. Mohamed
- de Jong Pim A.
- Lammers Jan-Willem J.
- Mali Willem PThM
- Schmidt Michael
- de Koning Harry J.
- van der Aalst Carlijn
- Oudkerk Matthijs
- Vliegenthart Rozemarijn
- van Ginneken Bram
- van Rikxoort Eva M.
- Zanen Pieter
DOIAbstract
/FVC <70% and/or < the lower limit of normal (LLN)) in (heavy) smokers. <80% predicted, were excluded. Multivariate regression analysis correcting for covariates was used to asses the extent of emphysema, airway wall thickening and gas trapping according to three groups of airflow limitation. percentile, −920.6 HU versus −912.2 HU; a higher Pi10, 2.87 mm versus 2.57 mm; and a higher E/I-ratio, 88.6% versus 85.6% (all p<0.001)./FVC<70%, but above the LLN, have a significant greater degree of structural lung changes on CT compared to subjects without airflow limitation
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