AbstractThe association structures formed by cationic liposomes and DNA-plasmids have been successfully employed as gene carriers in transfection assays. In the present study such complexes was studied by cryo-TEM (cryo-transmission electron microscopy). Cationic liposomes made up by DOPE (dioleoylphosphatidylethanolamine) and various amounts of three different cationic surfactants were investigated. The cryo-TEM analysis suggests that an excess of lipid in terms of charge, leads to entrapment of the DNA molecules between the lamellas in clusters of aggregated multilamellar structures. With increasing amounts of DNA free or loosely bound plasmids were found in the vicinity of the complexes. The importance of the choice of surfactant, as rep...
A double approach, experimental and theoretical, has been followed to characterize from a physicoche...
The structural and fusogenic properties of large unilamellar vesicles (LUVs) composed of the cationi...
DNA-cationic liposome complexes as possible vehicles for gene delivery is currently an important iss...
AbstractThe association structures formed by cationic liposomes and DNA-plasmids have been successfu...
Cationic liposomes spontaneously interact with the negatively charged DNA to form a stable complex t...
AbstractStructures formed during interaction of cationic liposomes and plasmid DNA were studied by f...
International audienceThe structure of complexes made from DNA and suitable lipids (lipoplex, Lx) wa...
Cationic liposomes are being increasingly studied as delivery vehicles for bioactive agents such as ...
Cryoelectron microscopy has been used to study the reorganization of unilamellar cationic lipid vesi...
In the procedure for cationic liposome-mediated transfection, the cationic lipid is usually mixed wi...
Studies published between 2001 and 2005 that utilise cryogenic transmission electron microscopy as a...
A study related to the development and characterization of a new gene delivery system was performed....
DNA- cationic amphiphile and DNA-cationic polymer systems were studied with respect to the intermole...
AbstractCryoelectron microscopy has been used to study the reorganization of unilamellar cationic li...
A double approach, experimental and theoretical, has been followed to characterize from a physicoche...
A double approach, experimental and theoretical, has been followed to characterize from a physicoche...
The structural and fusogenic properties of large unilamellar vesicles (LUVs) composed of the cationi...
DNA-cationic liposome complexes as possible vehicles for gene delivery is currently an important iss...
AbstractThe association structures formed by cationic liposomes and DNA-plasmids have been successfu...
Cationic liposomes spontaneously interact with the negatively charged DNA to form a stable complex t...
AbstractStructures formed during interaction of cationic liposomes and plasmid DNA were studied by f...
International audienceThe structure of complexes made from DNA and suitable lipids (lipoplex, Lx) wa...
Cationic liposomes are being increasingly studied as delivery vehicles for bioactive agents such as ...
Cryoelectron microscopy has been used to study the reorganization of unilamellar cationic lipid vesi...
In the procedure for cationic liposome-mediated transfection, the cationic lipid is usually mixed wi...
Studies published between 2001 and 2005 that utilise cryogenic transmission electron microscopy as a...
A study related to the development and characterization of a new gene delivery system was performed....
DNA- cationic amphiphile and DNA-cationic polymer systems were studied with respect to the intermole...
AbstractCryoelectron microscopy has been used to study the reorganization of unilamellar cationic li...
A double approach, experimental and theoretical, has been followed to characterize from a physicoche...
A double approach, experimental and theoretical, has been followed to characterize from a physicoche...
The structural and fusogenic properties of large unilamellar vesicles (LUVs) composed of the cationi...
DNA-cationic liposome complexes as possible vehicles for gene delivery is currently an important iss...