Effect on Postpartum Hemorrhage of Prophylactic Oxytocin (10 IU) by Injection by Community Health Officers in Ghana: A Community-Based, Cluster-Randomized Trial
- Stanton Cynthia K.
- Newton Samuel
- Mullany Luke C.
- Cofie Patience
- Tawiah Agyemang Charlotte
- Adiibokah Edward
- Amenga-Etego Seeba
- Darcy Niamh
- Khan Sadaf
- Armbruster Deborah
- Gyapong John
- Owusu-Agyei Seth
DOIAbstract
Oxytocin (10 IU) is the drug of choice for prevention of postpartum hemorrhage (PPH). Its use has generally been restricted to medically trained staff in health facilities. We assessed the effectiveness, safety, and feasibility of PPH prevention using oxytocin injected by peripheral health care providers without midwifery skills at home births.This community-based, cluster-randomized trial was conducted in four rural districts in Ghana. We randomly allocated 54 community health officers (stratified on district and catchment area distance to a health facility: ≥10 km versus <10 km) to intervention (one injection of oxytocin [10 IU] one minute after birth) and control (no provision of prophylactic oxytocin) arms. Births attended by a communit...
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