A Molecular Epidemiological and Genetic Diversity Study of Tuberculosis in Ibadan, Nnewi and Abuja, Nigeria
- Lawson Lovett
- Zhang Jian
- Gomgnimbou Michel K.
- Abdurrahman Saddiq T.
- Le Moullec Stéphanie
- Mohamed Fatima
- Uzoewulu Gertrude N.
- Sogaolu Olumide M.
- Goh Khye Seng
- Emenyonu Nnamdi
- Refrégier Guislaine
- Cuevas Luis E.
- Sola Christophe
DOIAbstract
Nigeria has the tenth highest burden of tuberculosis (TB) among the 22 TB high-burden countries in the world. This study describes the biodiversity and epidemiology of drug-susceptible and drug-resistant TB in Ibadan, Nnewi and Abuja, using 409 DNAs extracted from culture positive TB isolates. West African 1. The recent transmission rate of TB was 38%. This large study shows that the recent transmission of TB in Nigeria is high, without major regional differences, with MDR-TB clusters. Improvement in the TB control programme is imperative to address the TB control problem in Nigeria
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