The Association between Subclinical Atherosclerosis and Uterine Fibroids

To explore the atherogenic hypothesis of uterine fibroids among Chinese women.In a case-control study, 335 patients confirmed by ultrasound or hysterectomy surgery and 539 controls were enrolled between October 1, 2009 and April 1, 2012. Unconditional logistic regressions were used to calculate the odds ratios (ORs) for the associations of subclinical atherogenic and cardiovascular risk parameters with uterine fibroids in the overall case group and hysterectomy-confirmed case group, respectively. = 0.014). Moreover, the effect of homocysteine concentration was not observed in this group.These findings suggest that women with uterine fibroids might have an increased risk of subclinical atherosclerosis