In this study, we examined the concentration of serum immunoglobulin free light chains (FLCs) in systemic lupus erythematosus (SLE) patients and investigated its association with various disease parameters in order to evaluate the role of FLCs as a potential biomarker in SLE. Furthermore, FLCs’ association with Epstein-Barr virus (EBV) antibodies was examined.Using a nephelometric assay, κFLC and λFLC concentrations were quantified in sera from 45 SLE patients and 40 healthy controls. SLE patients with renal insufficiency were excluded in order to preclude high concentrations of serum FLCs due to decreased clearance.Serum FLC concentrations were significantly elevated in SLE patients compared to healthy controls (p<0.0001) also after adjust...
Copyright © 2013 Aurélie Grados et al.This is an open access article distributed under the Creative...
BACKGROUND: We evaluated whether serum leucine-rich α2-glycoprotein (LRG) is associated with disease...
9 páginasObjective There are no laboratory tools that detect early flares in systemic lupus erythema...
In this study, we examined the concentration of serum immunoglobulin free light chains (FLCs) in sys...
In this study, we examined the concentration of serum immunoglobulin free light chains (FLCs) in sys...
The concentration of urinary free light chains was measured in 61 patients with systemic lupus eryth...
Circulating free light chains (FLCs), considered biomarkers of B cell activity, are frequently eleva...
<p>Correlation between total immunoglobulin levels and total FLC, λFLC and κFLC levels in SLE patien...
International audienceHigh amount of polyclonal free light chains (FLC) are reported in systemic aut...
The study of free light chains (FLCs) has grown as area of enormous interest for many clinicians wit...
AIM: Humoral immunity and B cells are thought to play an important role in the pathophysiology of t...
Objectives. Serum immunoglobulin free light chains (FLCs) are frequently elevated in B-cell-mediated...
Introduction: Active systemic lupus erythematosus ( SLE) and infection are often hard to distinguish...
Infections may act as environmental triggers for the induction of systemic lupus erythematosus (SLE)...
Several reports have highlighted the abnormal increments of serum immunoglobulin free light chains (...
Copyright © 2013 Aurélie Grados et al.This is an open access article distributed under the Creative...
BACKGROUND: We evaluated whether serum leucine-rich α2-glycoprotein (LRG) is associated with disease...
9 páginasObjective There are no laboratory tools that detect early flares in systemic lupus erythema...
In this study, we examined the concentration of serum immunoglobulin free light chains (FLCs) in sys...
In this study, we examined the concentration of serum immunoglobulin free light chains (FLCs) in sys...
The concentration of urinary free light chains was measured in 61 patients with systemic lupus eryth...
Circulating free light chains (FLCs), considered biomarkers of B cell activity, are frequently eleva...
<p>Correlation between total immunoglobulin levels and total FLC, λFLC and κFLC levels in SLE patien...
International audienceHigh amount of polyclonal free light chains (FLC) are reported in systemic aut...
The study of free light chains (FLCs) has grown as area of enormous interest for many clinicians wit...
AIM: Humoral immunity and B cells are thought to play an important role in the pathophysiology of t...
Objectives. Serum immunoglobulin free light chains (FLCs) are frequently elevated in B-cell-mediated...
Introduction: Active systemic lupus erythematosus ( SLE) and infection are often hard to distinguish...
Infections may act as environmental triggers for the induction of systemic lupus erythematosus (SLE)...
Several reports have highlighted the abnormal increments of serum immunoglobulin free light chains (...
Copyright © 2013 Aurélie Grados et al.This is an open access article distributed under the Creative...
BACKGROUND: We evaluated whether serum leucine-rich α2-glycoprotein (LRG) is associated with disease...
9 páginasObjective There are no laboratory tools that detect early flares in systemic lupus erythema...