Natural History of Malignant Bone Disease in Renal Cancer: Final Results of an Italian Bone Metastasis Survey
- Santini Daniele
- Procopio Giuseppe
- Porta Camillo
- Ibrahim Toni
- Barni Sandro
- Mazzara Calogero
- Fontana Andrea
- Berruti Alfredo
- Berardi Rossana
- Vincenzi Bruno
- Ortega Cinzia
- Ottaviani Davide
- Carteni Giacomo
- Lanzetta Gaetano
- Virzì Vladimir
- Santoni Matteo
- Silvestris Nicola
- Satolli Maria Antonietta
- Collovà Elena
- Russo Antonio
- Badalamenti Giuseppe
- Fedeli Stefano Luzi
- Tanca Francesca Maria
- Adamo Vincenzo
- Maiello Evaristo
- Sabbatini Roberto
- Felici Alessandra
- Cinieri Saverio
- Tonini Giuseppe
- Bracarda Sergio
DOIAbstract
Bone metastasis represents an increasing clinical problem in advanced renal cell carcinoma (RCC) as disease-related survival improves. There are few data on the natural history of bone disease in RCC.Data on clinicopathology, survival, skeletal-related events (SREs), and bone-directed therapies for 398 deceased RCC patients (286 male, 112 female) with evidence of bone metastasis were statistically analyzed.<0.05).RCC patients with bone metastasis are at continuous risk of SREs, and in this survey ZOL effectively reduced this risk
Add to ORKG