Scarred vocal folds result in irregular vibrations during phonation due to stiffness of the vocal fold mucosa. To date, a completely satisfactory corrective procedure has yet to be achieved. We hypothesize that a potential treatment option for this disease is to replace scarred vocal folds with organotypic mucosa. The purpose of this study is to regenerate vocal fold mucosa using a tissue-engineered structure with autologous oral mucosal cells.Animal experiment using eight beagles (including three controls).A 3 mm by 3 mm specimen of canine oral mucosa was surgically excised and divided into epithelial and subepithelial tissues. Epithelial cells and fibroblasts were isolated and cultured separately. The proliferated epithelial cells were co...
Background. The aim of the study was to assess the histological effects of autologous infusion of ad...
SummaryMany techniques were applied to treat patients with sulcus vocalis and scarred vocal folds. T...
Patients with laryngeal disorders may have severe morbidity relating to swallowing, vocalization, an...
Objectives Scarred vocal folds result in irregular vibrations during phonation due to stiffness of t...
ObjectiveA vibratory vocal fold replacement would introduce a new treatment paradigm for structural ...
Tissue engineering has revealed the potential to regenerate injured vocal folds, and identification ...
Tissue engineering has revealed the potential to regenerate injured vocal folds, and identification ...
Vocal fold epithelial cells are very difficult to study as the vocal fold epithelial cell lines do n...
<p>A tissue-engineered vocal fold mucosa was successfully fabricated (20 mm diameter).</p
We have developed a cell-based outer vocal fold replacement (COVR) as a potential therapy to improve...
Objectives:Cell therapies using mesenchymal stromal cells (MSCs) have been proposed as a promising n...
We have developed a cell-based outer vocal fold replacement (COVR) as a potential therapy to improve...
<p>A 3 mm by 3 mm specimen of buccal mucosal tissue was excised. The mucosal section was divided int...
<p>Hematoxylin and Eosin staining revealed that the tissue-engineered vocal fold mucosa consisted of...
Objectives/hypothesisOne potential treatment for vocal fold injury or neoplasia is to replace the en...
Background. The aim of the study was to assess the histological effects of autologous infusion of ad...
SummaryMany techniques were applied to treat patients with sulcus vocalis and scarred vocal folds. T...
Patients with laryngeal disorders may have severe morbidity relating to swallowing, vocalization, an...
Objectives Scarred vocal folds result in irregular vibrations during phonation due to stiffness of t...
ObjectiveA vibratory vocal fold replacement would introduce a new treatment paradigm for structural ...
Tissue engineering has revealed the potential to regenerate injured vocal folds, and identification ...
Tissue engineering has revealed the potential to regenerate injured vocal folds, and identification ...
Vocal fold epithelial cells are very difficult to study as the vocal fold epithelial cell lines do n...
<p>A tissue-engineered vocal fold mucosa was successfully fabricated (20 mm diameter).</p
We have developed a cell-based outer vocal fold replacement (COVR) as a potential therapy to improve...
Objectives:Cell therapies using mesenchymal stromal cells (MSCs) have been proposed as a promising n...
We have developed a cell-based outer vocal fold replacement (COVR) as a potential therapy to improve...
<p>A 3 mm by 3 mm specimen of buccal mucosal tissue was excised. The mucosal section was divided int...
<p>Hematoxylin and Eosin staining revealed that the tissue-engineered vocal fold mucosa consisted of...
Objectives/hypothesisOne potential treatment for vocal fold injury or neoplasia is to replace the en...
Background. The aim of the study was to assess the histological effects of autologous infusion of ad...
SummaryMany techniques were applied to treat patients with sulcus vocalis and scarred vocal folds. T...
Patients with laryngeal disorders may have severe morbidity relating to swallowing, vocalization, an...