Triton X-100 catalyzed synthesis of α-aminophosphonates

Reddy, Nemallapudi Bakthavatchala
Sundar, Chereddy Syama
Rani, Chinthaparthi Radha
Rao, Kunda Uma Maheswara
Nayak, Sandip Kumar
Reddy, Cirandur Suresh

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Publication date

September 2016

DOI

10.1016/j.arabjc.2011.07.025

Publisher

Production and hosting by Elsevier B.V. on behalf of King Saud University.

Abstract

AbstractSynthesis of α-aminophosphonates by a three-component condensation of an aldehyde, amines and dialkyl phosphites in the presence of a non-ionic surfactant Triton X-100 catalyst at 70°C in aqueous medium is accomplished. The advantages are high yield, mild reaction conditions, simple work-up and eco-friendliness. All the newly-synthesized compounds (4a–j) exhibited moderate in vitro antibacterial and antifungal activities

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Triton X-100 catalyzed synthesis of α-aminophosphonates

Abstract

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Triton X-100 catalyzed synthesis of α-aminophosphonates

Abstract

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