Is Associated with the Development, Progression and Poor Outcome of Gastric Cancer

polymorphisms is associated with the development and progression of gastric cancer and its prognosis in Chinese patients.I polymorphisms were analyzed in 510 Chinese patients with gastric cancer and 510 age- and sex- matched healthy controls by PCR-RFLP. Odds ratios were estimated by multivariate logistic regression, and the lifetime was calculated by Kaplan-Meier survival curves. In addition, a meta-analysis was also conducted to verify the findings.I polymorphism was associated with a significantly increased risk of gastric cancer.I polymorphism is associated with increased risk of development, progression and poor prognosis of gastric cancer in Chinese patients. Pooled data from 13 studies, mainly in Asian countries, are in agreement with our findings