Enhances Adaptive Immune Responses to a Bacterial Antigen
- Hansen Jonathan J.
- Huang Yong
- Peterson Daniel A.
- Goeser Laura
- Fan Ting-Jia
- Chang Eugene B.
- Sartor R. Balfour
DOIAbstract
in causing disease in Tg rats is unknown nor is much known about how gut microbes respond to host inflammation. gene. from Tg rats and include a SusC homolog that induces adaptive immune responses in Tg rats. induces colitis in HLA-B27 Tg rats, which is associated with regulation of bacterial genes in metabolic and nutrient binding pathways that may affect host immune responses. These studies of the host-microbial dialogue may lead to the identification of novel microbial targets for IBD therapies
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