Prevention of Contrast-Induced Acute Kidney Injury: Is Simple Oral Hydration Similar To Intravenous? A Systematic Review of the Evidence

Pre-procedural intravenous fluid administration is an effective prophylaxis measure for contrast-induced acute kidney injury. For logistical ease, the oral route is an alternative to the intravenous. The objective of this study was to compare the efficacy of the oral to the intravenous route in prevention of contrast-induced acute kidney injury. quarter 2011). Two reviewers identified relevant trials and abstracted data.Trials including patients undergoing a contrast enhanced procedure.Randomised controlled trial; adult (>18 years) population; comparison of oral versus intravenous volume expansion.Oral route of volume expansion compared to the intravenous route.Any measure of acute kidney injury, need for renal replacement therapy, hospitalization and death. = 0).Small number of studies identified; lack of hard clinical outcomes.The oral route may be as effective as the intravenous route for volume expansion for contrast-induced acute kidney injury prevention. Adequately powered trials with hard endpoints should be done given the potential advantages of oral (e.g. reduced patient burden and cost) over intravenous volume expansion