Fatty Fish Intake Decreases Lipids Related to Inflammation and Insulin Signaling—A Lipidomics Approach
- Lankinen Maria
- Schwab Ursula
- Erkkilä Arja
- Seppänen-Laakso Tuulikki
- Hannila Marja-Leena
- Mussalo Hanna
- Lehto Seppo
- Uusitupa Matti
- Gylling Helena
- Orešič Matej
DOIAbstract
The evidence of the multiple beneficial health effects of fish consumption is strong, but physiological mechanisms behind these effects are not completely known. Little information is available on the effects of consumption of different type of fish. The aim of this study was to investigate how fatty fish or lean fish in a diet affect serum lipidomic profiles in subjects with coronary heart disease.-value <0.05).The 8-week consumption of fatty fish decreased lipids which are potential mediators of lipid-induced insulin resistance and inflammation, and may be related to the protective effects of fatty fish on the progression of atherosclerotic vascular diseases or insulin resistance
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