Adiponectin Gene Polymorphisms and Acute Respiratory Distress Syndrome Susceptibility and Mortality

) have been examined for relationships with obesity, insulin resistance and diabetes, cardiovascular disease, and to circulating adipokine levels, but many gaps in knowledge remain. The current study aims to assess the association between potentially functional polymorphisms in adiponectin-related genes with acute respiratory distress syndrome (ARDS) risk and mortality. were successfully genotyped. Of these, 9 SNPs were hypothesized to be functional based on their location (promoter, exon, or 3′ untranslated region). These 9 SNPs were analyzed for association with ARDS case status and mortality among ARDS cases. = 0.029). may impact survival in ARDS. Further studies are required to replicate these results and to correlate genotype with circulating adiponectin levels