spp. CD4+ T cells play critical roles in both host immune responses against parasitic infection and immunopathology in schistosomiasis,and coordinate many types of immune cells that contribute to fibrosis. ICOSL plays an important role in controlling specific aspects of T cell activation, differentiation, and function. Previous work has suggested that ICOS is essential for Th17 cell development. However, the immunopathogenesis of this pathway in schistosomiasis fibrosisis still unclear. infection, and investigated the immune responses and pathology of ICOSL KO mice in these models. The results showed that ICOSL KO mice exhibited improved survival, reduced liver granulomatous inflammation around parasite eggs, markedly inhibited hepatic fib...
The disease manifestations of schistosomiasis arise from the mammalian host-mediated type 2 T-helper...
Cytokines are important in the cell-mediated response to Schistosoma mansoni eggs. We have found tha...
We have used IL-10 gene knockout mice (IL-10T) to examine the role of endogenous IL-10 in the down-m...
spp. CD4+ T cells play critical roles in both host immune responses against parasitic infection and...
Cytokine regulation of schistosome-induced granuloma and fibrosis. Schistosomiasis mansoni, a major ...
CBA/J mice infected with the helminth Schistosoma mansoni develop severe CD4 T cell-mediated hepatic...
Infection with schistosome helminths is associated with granulomatous inflammation that forms around...
In murine schistosomiasis mansoni, pronounced CD4 T cell-mediated, egg-induced, hepato-intestinal im...
Schistosoma mansoni infections are associated with a strong Th2 cytokine response. Treatment of mice...
Schistosomiasis continues to be a significant cause of parasitic morbidity and mortality worldwide. ...
infection or whether these cells and their defining IL-17 cytokine mediate host protective response...
International audienceT-helper (Th) 17 cells that express lineage-specific transcription factor RORC...
International audienceT-helper (Th) 17 cells that express lineage-specific transcription factor RORC...
Background. Schistosome infections are often clinically silent, but some individuals develop severe ...
Schistosomiasis continues to be one of the most prevalent parasitie infections in the world. In schi...
The disease manifestations of schistosomiasis arise from the mammalian host-mediated type 2 T-helper...
Cytokines are important in the cell-mediated response to Schistosoma mansoni eggs. We have found tha...
We have used IL-10 gene knockout mice (IL-10T) to examine the role of endogenous IL-10 in the down-m...
spp. CD4+ T cells play critical roles in both host immune responses against parasitic infection and...
Cytokine regulation of schistosome-induced granuloma and fibrosis. Schistosomiasis mansoni, a major ...
CBA/J mice infected with the helminth Schistosoma mansoni develop severe CD4 T cell-mediated hepatic...
Infection with schistosome helminths is associated with granulomatous inflammation that forms around...
In murine schistosomiasis mansoni, pronounced CD4 T cell-mediated, egg-induced, hepato-intestinal im...
Schistosoma mansoni infections are associated with a strong Th2 cytokine response. Treatment of mice...
Schistosomiasis continues to be a significant cause of parasitic morbidity and mortality worldwide. ...
infection or whether these cells and their defining IL-17 cytokine mediate host protective response...
International audienceT-helper (Th) 17 cells that express lineage-specific transcription factor RORC...
International audienceT-helper (Th) 17 cells that express lineage-specific transcription factor RORC...
Background. Schistosome infections are often clinically silent, but some individuals develop severe ...
Schistosomiasis continues to be one of the most prevalent parasitie infections in the world. In schi...
The disease manifestations of schistosomiasis arise from the mammalian host-mediated type 2 T-helper...
Cytokines are important in the cell-mediated response to Schistosoma mansoni eggs. We have found tha...
We have used IL-10 gene knockout mice (IL-10T) to examine the role of endogenous IL-10 in the down-m...