) rearrangement in selected advanced non-small cell lung cancer (NSCLC), to compare the application of different ALK detection methods, and especially evaluate a possible association between ALK expression and clinical outcomes in crizotinib-treated patients.) mutation. alterations showed difference in ALK expression, response to EGFR and ALK inhibitors, and overall survival.
Introduction. Translocations of ALK receptor tyrosine kinase occur in approximately 5–9 % of lung ad...
The knowledge of oncogene addiction in non small cell lung carcinoma (NSCLC) involving EGFR, ALK and...
Rearrangements in anaplastic lymphoma kinase (ALK) gene and echinoderm microtubule-associated protei...
Background: This study aimed to elucidate clinical significance of anaplastic lymphoma kinase (ALK) ...
Patients with advanced-stage non-small cell lung carcinoma (NSCLC) harboring an ALK rearrangement, d...
Pharmacologic agents that target protein products of oncogenes in tumors are playing an increasing c...
Background: In non-small cell lung cancer (NSCLC), anaplastic lymphoma kinase (ALK) rearrangement ch...
ABSTRACT: To date, ALK-rearrangement is a molecular target in several cancers, i.e. NSCLC. The drama...
It was only 3 years ago that an acquired translocation of EML4 with ALK leading to the expression of...
The recent approval of crizotinib for the treatment of anaplastic lymphoma kinase (ALK)-rearranged a...
The recent approval of crizotinib for the treatment of anaplastic lymphoma kinase (ALK)-rearranged a...
The anaplastic lymphoma kinase (ALK) gene rearrangement identifies a distinct molecular subset in no...
Systemic chemotherapy, genotype-based targeted therapies and immunotherapy are widely used in the tr...
Non-small cell lung cancers (NSCLCs) harboring anaplastic lymphoma kinase (ALK) rearrangement are ge...
Advances in our understanding of tumour biology have encouraged reassessment of tumour classificatio...
Introduction. Translocations of ALK receptor tyrosine kinase occur in approximately 5–9 % of lung ad...
The knowledge of oncogene addiction in non small cell lung carcinoma (NSCLC) involving EGFR, ALK and...
Rearrangements in anaplastic lymphoma kinase (ALK) gene and echinoderm microtubule-associated protei...
Background: This study aimed to elucidate clinical significance of anaplastic lymphoma kinase (ALK) ...
Patients with advanced-stage non-small cell lung carcinoma (NSCLC) harboring an ALK rearrangement, d...
Pharmacologic agents that target protein products of oncogenes in tumors are playing an increasing c...
Background: In non-small cell lung cancer (NSCLC), anaplastic lymphoma kinase (ALK) rearrangement ch...
ABSTRACT: To date, ALK-rearrangement is a molecular target in several cancers, i.e. NSCLC. The drama...
It was only 3 years ago that an acquired translocation of EML4 with ALK leading to the expression of...
The recent approval of crizotinib for the treatment of anaplastic lymphoma kinase (ALK)-rearranged a...
The recent approval of crizotinib for the treatment of anaplastic lymphoma kinase (ALK)-rearranged a...
The anaplastic lymphoma kinase (ALK) gene rearrangement identifies a distinct molecular subset in no...
Systemic chemotherapy, genotype-based targeted therapies and immunotherapy are widely used in the tr...
Non-small cell lung cancers (NSCLCs) harboring anaplastic lymphoma kinase (ALK) rearrangement are ge...
Advances in our understanding of tumour biology have encouraged reassessment of tumour classificatio...
Introduction. Translocations of ALK receptor tyrosine kinase occur in approximately 5–9 % of lung ad...
The knowledge of oncogene addiction in non small cell lung carcinoma (NSCLC) involving EGFR, ALK and...
Rearrangements in anaplastic lymphoma kinase (ALK) gene and echinoderm microtubule-associated protei...