In this issue of Neuron, Polosukhina et al. (2012) intravitreally deliver the light-activatable molecule acrylamide-azobenzene-quaternary ammonium (AAQ) to the eyes of mice with end-stage retinal degeneration. Results show that, with the appropriate illumination, AAQ restores light sensitivity and visual behavior
SummaryRetinitis pigmentosa (RP) and age-related macular degeneration (AMD) are blinding diseases ca...
SummaryThe death of photoreceptor cells caused by retinal degenerative diseases often results in a c...
Retinitis pigmentosa results in blindness due to degeneration of photoreceptors, but spares other re...
In this issue of Neuron, Polosukhina et al. (2012) intravitreally deliver the light-activatable mole...
SummaryRetinitis pigmentosa (RP) and age-related macular degeneration (AMD) are degenerative blindin...
This dissertation addresses two non-genetic therapeutic approaches for treating inherited retinal di...
AbstractPhotoswitches are traditional pharmacologic agonists, antagonists, or channel blockers that ...
(RGCs). Intraocular injection of AAQ restores the pupillary light reflex and locomotory light avoida...
Azobenzene photoswitches confer light sensitivity onto retinal ganglion cells (RGCs) in blind mice, ...
Most inherited forms of blindness are caused by mutations that lead to photoreceptor cell death but ...
Retinitis pigmentosa (RP) and age-related macular degeneration (AMD) are blinding diseases caused by...
The death of photoreceptor cells caused by retinal degenerative diseases often results in a complete...
Rhodopsin (RHO) mutations are responsible for 25–40% of the dominant cases of retinitis pigmentosa (...
Most inherited retinal dystrophies display progressive photoreceptor cell degeneration leading to se...
SummaryMany retinal dystrophies result in photoreceptor loss, but the inner retinal neurons can surv...
SummaryRetinitis pigmentosa (RP) and age-related macular degeneration (AMD) are blinding diseases ca...
SummaryThe death of photoreceptor cells caused by retinal degenerative diseases often results in a c...
Retinitis pigmentosa results in blindness due to degeneration of photoreceptors, but spares other re...
In this issue of Neuron, Polosukhina et al. (2012) intravitreally deliver the light-activatable mole...
SummaryRetinitis pigmentosa (RP) and age-related macular degeneration (AMD) are degenerative blindin...
This dissertation addresses two non-genetic therapeutic approaches for treating inherited retinal di...
AbstractPhotoswitches are traditional pharmacologic agonists, antagonists, or channel blockers that ...
(RGCs). Intraocular injection of AAQ restores the pupillary light reflex and locomotory light avoida...
Azobenzene photoswitches confer light sensitivity onto retinal ganglion cells (RGCs) in blind mice, ...
Most inherited forms of blindness are caused by mutations that lead to photoreceptor cell death but ...
Retinitis pigmentosa (RP) and age-related macular degeneration (AMD) are blinding diseases caused by...
The death of photoreceptor cells caused by retinal degenerative diseases often results in a complete...
Rhodopsin (RHO) mutations are responsible for 25–40% of the dominant cases of retinitis pigmentosa (...
Most inherited retinal dystrophies display progressive photoreceptor cell degeneration leading to se...
SummaryMany retinal dystrophies result in photoreceptor loss, but the inner retinal neurons can surv...
SummaryRetinitis pigmentosa (RP) and age-related macular degeneration (AMD) are blinding diseases ca...
SummaryThe death of photoreceptor cells caused by retinal degenerative diseases often results in a c...
Retinitis pigmentosa results in blindness due to degeneration of photoreceptors, but spares other re...