AbstractV(D)J recombination assembles antigen receptor genes from component gene segments. We review findings that have shaped our current understanding of this remarkable mechanism, with a focus on two major reports—the first detailed comparison of germline and rearranged antigen receptor loci and the discovery of the recombination activating gene-1
During lymphocyte development, V(D)J recombination assembles antigen receptor genes from component V...
Variable (V), diversity (D), and joining (J) (V(D)J) recombination is the first determinant of antig...
International audienceChromosome breaks are dangerous business, carrying the risk of loss of genetic...
AbstractV(D)J recombination assembles antigen receptor genes from component gene segments. We review...
AbstractV(D)J recombination is of fundamental importance to the generation of diverse antigen recept...
International audienceThe V(D)J recombination machinery assembles antigen receptor genes from germli...
International audienceV(D)J recombination assembles antigen-specific immunoglobulin and T-cell recep...
International audienceV(D)J recombination assembles antigen receptor genes from germline V, D and J ...
Lymphocytes recognize a vast variety of pathogens by expressing a diverse repertoire of antigen rece...
A diverse antibody repertoire is the backbone of a successful adaptive immune response. This diversi...
Summary: The genes that encode immunoglobulins and T‐cell receptors must be assembled from the mult...
SummaryThe critical initial step in V(D)J recombination, binding of RAG1 and RAG2 to recombination s...
V(D)J recombination is the process that generates the primary antigen receptor repertoire of the ada...
B-cells and T-cells are major components of immunity that detect a large variety of antigens that en...
SummaryVariable (V), diversity (D), and joining (J) (V(D)J) recombination is the first determinant o...
During lymphocyte development, V(D)J recombination assembles antigen receptor genes from component V...
Variable (V), diversity (D), and joining (J) (V(D)J) recombination is the first determinant of antig...
International audienceChromosome breaks are dangerous business, carrying the risk of loss of genetic...
AbstractV(D)J recombination assembles antigen receptor genes from component gene segments. We review...
AbstractV(D)J recombination is of fundamental importance to the generation of diverse antigen recept...
International audienceThe V(D)J recombination machinery assembles antigen receptor genes from germli...
International audienceV(D)J recombination assembles antigen-specific immunoglobulin and T-cell recep...
International audienceV(D)J recombination assembles antigen receptor genes from germline V, D and J ...
Lymphocytes recognize a vast variety of pathogens by expressing a diverse repertoire of antigen rece...
A diverse antibody repertoire is the backbone of a successful adaptive immune response. This diversi...
Summary: The genes that encode immunoglobulins and T‐cell receptors must be assembled from the mult...
SummaryThe critical initial step in V(D)J recombination, binding of RAG1 and RAG2 to recombination s...
V(D)J recombination is the process that generates the primary antigen receptor repertoire of the ada...
B-cells and T-cells are major components of immunity that detect a large variety of antigens that en...
SummaryVariable (V), diversity (D), and joining (J) (V(D)J) recombination is the first determinant o...
During lymphocyte development, V(D)J recombination assembles antigen receptor genes from component V...
Variable (V), diversity (D), and joining (J) (V(D)J) recombination is the first determinant of antig...
International audienceChromosome breaks are dangerous business, carrying the risk of loss of genetic...
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