Substance Use (Alcohol, Areca Nut and Cigarette) Is Associated with Poor Prognosis of Esophageal Squamous Cell Carcinoma
- Wu I-Chen
- Wu Chun-Chieh
- Lu Chien-Yu
- Hsu Wen-Hung
- Wu Meng-Chieh
- Lee Jui-Ying
- Chou Shah-Hwa
- Lee Jang-Ming
- Chou Yi-Ping
- Wu Deng-Chyang
- Wu Ming-Tsang
DOIAbstract
Few studies have reported the association between lifestyle factors and prognosis of esophageal squamous cell carcinoma (ESCC) and among these, the effects of habitual areca nut chewing have never been examined. for trend = 0.01).Our study found that indulgence in more substances is a significant predictor of ESCC survival. Further mechanistic studies are necessary to elucidate how these substances lead to an adverse outcome
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