Study
- Hajarizadeh Behzad
- Grady Bart
- Page Kimberly
- Kim Arthur Y.
- McGovern Barbara H.
- Cox Andrea L.
- Rice Thomas M.
- Sacks-Davis Rachel
- Bruneau Julie
- Morris Meghan
- Amin Janaki
- Schinkel Janke
- Applegate Tanya
- Maher Lisa
- Hellard Margaret
- Lloyd Andrew R.
- Prins Maria
- Dore Gregory J.
- Grebely Jason
DOIAbstract
Understanding the patterns of HCV RNA levels during acute hepatitis C virus (HCV) infection provides insights into immunopathogenesis and is important for vaccine design. This study evaluated patterns of HCV RNA levels and associated factors among individuals with acute infection.-defined patterns of HCV RNA levels: i) spontaneous clearance, ii) partial viral control with persistence (≥1 log IU/mL decline in HCV RNA levels following peak) and iii) viral plateau with persistence (increase or <1 log IU/mL decline in HCV RNA levels following peak). Factors associated with HCV RNA patterns were assessed using multinomial logistic regression.) CC genotype was independently associated with partial viral control compared to viral plateau (adjusted...
Add to ORKG