in Ulcerative Colitis: Potential Pathogenic Entities?
- Thomson John M.
- Hansen Richard
- Berry Susan H.
- Hope Mairi E.
- Murray Graeme I.
- Mukhopadhya Indrani
- McLean Mairi H.
- Shen Zeli
- Fox James G.
- El-Omar Emad
- Hold Georgina L.
DOIAbstract
organisms in adults with and without UC. species prevalence was significantly higher in the UC group compared to the control group (30 of 77 versus 2 of 59, p<0.0001). PCR and FISH results were concordant in 74 (67.9%) of subjects. The majority of discordant results were attributable to a higher positivity rate with FISH than PCR. organisms warrant consideration as potential pathogenic entities in UC. Isolation of these organisms from colonic tissue is needed to enable interrogation of pathogenicity against established criteria
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