Germline stem cells are key to genome transmission to future generations. Over recent years, there have been numerous insights into the regulatory mechanisms that govern both germ cell specification and the maintenance of the germline in adults. Complex regulatory interactions with both the niche and the environment modulate germline stem cell function. This perspective highlights some examples of this regulation to illustrate the diversity and complexity of the mechanisms involved
Stem cells are powerful and promising tools in regenerative medicine. Understanding how stem cells a...
Stem cells are powerful and promising tools in regenerative medicine. Understanding how stem cells a...
AbstractMuch effort is being invested in defining the intrinsic and extrinsic factors that control s...
Germline stem cells are key to genome transmission to future generations. Over recent years, there h...
International audienceOur fascination for stem cells originates from their ability to divide asymmet...
Sperm and egg production requires a robust stem cell system that balances self-renewal with differen...
Germ cells are the special cells in the body that undergo meiosis to generate gametes and subsequent...
Human fertility is dependent upon the correct establishment and differentiation of the germline. Thi...
Adult stem cells replenish tissues during normal cellular turnover or injury. A stem cell divides as...
Stem cells have an enormous capacity of self-renewal, as well as the ability to differentiate into s...
Regulated activity of adult stem cells is essential for tis-sue homeostasis. Adult stem cell lineage...
Tissue-specific stem cells have the capacity to self-renew and differentiate into several types of f...
All multicellular organisms constantly need to replace aged or damaged cells. This vital task of tis...
AbstractThe passage of an individual's genome to future generations is essential for the maintenance...
The multipotentiality and self-renewal ability of stem cells are controlled by intrinsic genetic pat...
Stem cells are powerful and promising tools in regenerative medicine. Understanding how stem cells a...
Stem cells are powerful and promising tools in regenerative medicine. Understanding how stem cells a...
AbstractMuch effort is being invested in defining the intrinsic and extrinsic factors that control s...
Germline stem cells are key to genome transmission to future generations. Over recent years, there h...
International audienceOur fascination for stem cells originates from their ability to divide asymmet...
Sperm and egg production requires a robust stem cell system that balances self-renewal with differen...
Germ cells are the special cells in the body that undergo meiosis to generate gametes and subsequent...
Human fertility is dependent upon the correct establishment and differentiation of the germline. Thi...
Adult stem cells replenish tissues during normal cellular turnover or injury. A stem cell divides as...
Stem cells have an enormous capacity of self-renewal, as well as the ability to differentiate into s...
Regulated activity of adult stem cells is essential for tis-sue homeostasis. Adult stem cell lineage...
Tissue-specific stem cells have the capacity to self-renew and differentiate into several types of f...
All multicellular organisms constantly need to replace aged or damaged cells. This vital task of tis...
AbstractThe passage of an individual's genome to future generations is essential for the maintenance...
The multipotentiality and self-renewal ability of stem cells are controlled by intrinsic genetic pat...
Stem cells are powerful and promising tools in regenerative medicine. Understanding how stem cells a...
Stem cells are powerful and promising tools in regenerative medicine. Understanding how stem cells a...
AbstractMuch effort is being invested in defining the intrinsic and extrinsic factors that control s...