In this issue of Immunity, Lee et al. (2010) demonstrate that the mammalian Target of Rapamycin Complex 2 promotes the differentiation of T helper 1 (Th1) cells via the kinase Akt, whereas it independently fosters Th2 cell generation via another kinase, PKC-θ
During a T cell response, the effector CTL pool contains two cellular subsets: short-lived effector ...
Invariant NKT (iNKT) cells play critical roles in bridging innate and adaptive immunity. The Raptor ...
Although Pim-1 or Pim-2 can contribute to lymphoid transformation when overexpressed, the physiologi...
In this issue of Immunity, Lee et al. (2010) demonstrate that the mammalian Target of Rapamycin Comp...
SummaryMany functions of the mammalian target of rapamycin (mTOR) complex 1 (mTORC1) have been defin...
T cells are an important part of the adaptive immune system and play critical roles in the eliminati...
The mammalian target of rapamycin (mTOR) is essential for Th cell proliferation and effector differe...
The decision of naive Th cells to assume the fate of effector or regulator Th cells heavily influenc...
The mechanistic Target of Rapamycin (mTOR) is an evolutionarily conserved serine/threonine kinase wh...
The mammalian target of rapamycin (mTOR) integrates signalling responses to growth factors and nutri...
In this issue of Immunity, Shi et al. (2008) identify a previously unknown requirement in T helper c...
In the two-signal model of T cell activation, the outcome of antigen recognition is determined by th...
Ag-dependent activation of naive T cells induces dramatic changes in cellular metabolism that are es...
The mammalian target of rapamycin (mTOR) kinase is a critical regulator of the differentiation of he...
CD4+ T helper (Th) precursor cells are activated by the antigenic stimulation of T cell receptor (TC...
During a T cell response, the effector CTL pool contains two cellular subsets: short-lived effector ...
Invariant NKT (iNKT) cells play critical roles in bridging innate and adaptive immunity. The Raptor ...
Although Pim-1 or Pim-2 can contribute to lymphoid transformation when overexpressed, the physiologi...
In this issue of Immunity, Lee et al. (2010) demonstrate that the mammalian Target of Rapamycin Comp...
SummaryMany functions of the mammalian target of rapamycin (mTOR) complex 1 (mTORC1) have been defin...
T cells are an important part of the adaptive immune system and play critical roles in the eliminati...
The mammalian target of rapamycin (mTOR) is essential for Th cell proliferation and effector differe...
The decision of naive Th cells to assume the fate of effector or regulator Th cells heavily influenc...
The mechanistic Target of Rapamycin (mTOR) is an evolutionarily conserved serine/threonine kinase wh...
The mammalian target of rapamycin (mTOR) integrates signalling responses to growth factors and nutri...
In this issue of Immunity, Shi et al. (2008) identify a previously unknown requirement in T helper c...
In the two-signal model of T cell activation, the outcome of antigen recognition is determined by th...
Ag-dependent activation of naive T cells induces dramatic changes in cellular metabolism that are es...
The mammalian target of rapamycin (mTOR) kinase is a critical regulator of the differentiation of he...
CD4+ T helper (Th) precursor cells are activated by the antigenic stimulation of T cell receptor (TC...
During a T cell response, the effector CTL pool contains two cellular subsets: short-lived effector ...
Invariant NKT (iNKT) cells play critical roles in bridging innate and adaptive immunity. The Raptor ...
Although Pim-1 or Pim-2 can contribute to lymphoid transformation when overexpressed, the physiologi...
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