p53 is a key tumor suppressor protein that has numerous functions. Its primary mode of action has generally been ascribed to the induction of cell-cycle arrest, apoptosis, or senescence upon stress. Li et al. challenge this dogma with evidence that all three of these programs are dispensable for p53's tumor suppressive role
Activation of the tumour suppressor p53 upon cellular stress can induce a number of different cellul...
The tumor suppressor p53 regulates different cellular pathways involved in cell survival, DNA repair...
p53 is a major tumor suppressor that integrates diverse types of signaling in mammalian cells. In re...
p53 is a key tumor suppressor protein that has numerous functions. Its primary mode of action has ge...
SummaryThe p53 tumor suppressor governs multiple cell-intrinsic programs, including cell-cycle arres...
p53 has been studied intensively as a major tumour suppressor that detects oncogenic events in cance...
TP53, encoding p53, is one of the most famous tumor suppressor genes. The majority of human cancers ...
The TP53 tumor suppressor is the most frequently mutated gene in human cancer. p53 suppresses tumori...
The p53 tumor suppressor acts to integrate multiple stress signals into a series of diverse antiprol...
3noForty years of research have established that the p53 tumor suppressor provides a major barrier t...
As a key transcription factor, the evolutionarily conserved tumor suppressor p53 (encoded by TP53) p...
The mechanisms by which p53 suppresses tumor growth remain ill defined. In this issue of Cell Report...
The p53 tumour suppressor is the most frequently mutated gene in human cancer. This transcription fa...
The tumor suppressor p53 regulates different cellular pathways involved in cell survival, DNA repair...
The tumor-suppressing function of p53 can be affected in a variety of manners. Here, we describe a n...
Activation of the tumour suppressor p53 upon cellular stress can induce a number of different cellul...
The tumor suppressor p53 regulates different cellular pathways involved in cell survival, DNA repair...
p53 is a major tumor suppressor that integrates diverse types of signaling in mammalian cells. In re...
p53 is a key tumor suppressor protein that has numerous functions. Its primary mode of action has ge...
SummaryThe p53 tumor suppressor governs multiple cell-intrinsic programs, including cell-cycle arres...
p53 has been studied intensively as a major tumour suppressor that detects oncogenic events in cance...
TP53, encoding p53, is one of the most famous tumor suppressor genes. The majority of human cancers ...
The TP53 tumor suppressor is the most frequently mutated gene in human cancer. p53 suppresses tumori...
The p53 tumor suppressor acts to integrate multiple stress signals into a series of diverse antiprol...
3noForty years of research have established that the p53 tumor suppressor provides a major barrier t...
As a key transcription factor, the evolutionarily conserved tumor suppressor p53 (encoded by TP53) p...
The mechanisms by which p53 suppresses tumor growth remain ill defined. In this issue of Cell Report...
The p53 tumour suppressor is the most frequently mutated gene in human cancer. This transcription fa...
The tumor suppressor p53 regulates different cellular pathways involved in cell survival, DNA repair...
The tumor-suppressing function of p53 can be affected in a variety of manners. Here, we describe a n...
Activation of the tumour suppressor p53 upon cellular stress can induce a number of different cellul...
The tumor suppressor p53 regulates different cellular pathways involved in cell survival, DNA repair...
p53 is a major tumor suppressor that integrates diverse types of signaling in mammalian cells. In re...
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