Field Cancerization: Something New Under the Sun

  • Vanharanta, Sakari
  • Massagué, Joan
Publication date
June 2012
Publisher
Elsevier Inc.

Abstract

Mutations in keratinocyte and melanocyte precursors that are caused by extensive sun exposure are well-established contributors to skin cancer. Now Hu et al. provide evidence that the sun's harmful rays may also cause tumor-promoting epigenetic modifications in dermal fibroblasts, highlighting further the importance of tumor-stroma interactions in cancer

Extracted data

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