The growing interest in cancer metabolism is best demonstrated by the rapid progress made in studying isocitrate dehydrogenase (IDH) mutations since their discovery just over a year ago. In a recent study published in Nature, Dang et al. identified 2-hydroxyglutarate as a product of tumor-associated IDH mutants with potential oncogenic activities
Heterozygous hotspot mutations in isocitrate dehydrogenases (IDH) IDH1 or IDH2 are frequently observ...
Heterozygous hotspot mutations in isocitrate dehydrogenases (IDH) IDH1 or IDH2 are frequently observ...
-dependent isocitrate dehydrogenase (IDH2). Several different amino acid substitutions recur at eith...
The growing interest in cancer metabolism is best demonstrated by the rapid progress made in studyin...
The growing interest in cancer metabolism is best demonstrated by the rapid progress made in studyin...
The growing interest in cancer metabolism is best demonstrated by the rapid progress made in studyin...
The discovery of somatic mutations in the gene encoding isocitrate dehydrogenase-1 (IDH1) in gliobla...
The discovery of somatic mutations in the gene encoding isocitrate dehydrogenase-1 (IDH1) in gliobla...
Mutations in the metabolic enzyme isocitrate dehydrogenase (IDH) have recently been identified as dr...
Isocitrate dehydrogenases (IDH) 1 and 2 are key metabolic enzymes that generate reduced nicotinamide...
Heterozygous hotspot mutations in isocitrate dehydrogenases (IDH) IDH1 or IDH2 are frequently observ...
Malignant gliomas are the most common primary brain tumours in adults. Due to their diffuse nature a...
Malignant gliomas are the most common primary brain tumours in adults. Due to their diffuse nature a...
Heterozygous hotspot mutations in isocitrate dehydrogenases (IDH) IDH1 or IDH2 are frequently observ...
In 2009, the discovery of isocitrate dehydrogenase (IDH) mutations in gliomas is a powerful example ...
Heterozygous hotspot mutations in isocitrate dehydrogenases (IDH) IDH1 or IDH2 are frequently observ...
Heterozygous hotspot mutations in isocitrate dehydrogenases (IDH) IDH1 or IDH2 are frequently observ...
-dependent isocitrate dehydrogenase (IDH2). Several different amino acid substitutions recur at eith...
The growing interest in cancer metabolism is best demonstrated by the rapid progress made in studyin...
The growing interest in cancer metabolism is best demonstrated by the rapid progress made in studyin...
The growing interest in cancer metabolism is best demonstrated by the rapid progress made in studyin...
The discovery of somatic mutations in the gene encoding isocitrate dehydrogenase-1 (IDH1) in gliobla...
The discovery of somatic mutations in the gene encoding isocitrate dehydrogenase-1 (IDH1) in gliobla...
Mutations in the metabolic enzyme isocitrate dehydrogenase (IDH) have recently been identified as dr...
Isocitrate dehydrogenases (IDH) 1 and 2 are key metabolic enzymes that generate reduced nicotinamide...
Heterozygous hotspot mutations in isocitrate dehydrogenases (IDH) IDH1 or IDH2 are frequently observ...
Malignant gliomas are the most common primary brain tumours in adults. Due to their diffuse nature a...
Malignant gliomas are the most common primary brain tumours in adults. Due to their diffuse nature a...
Heterozygous hotspot mutations in isocitrate dehydrogenases (IDH) IDH1 or IDH2 are frequently observ...
In 2009, the discovery of isocitrate dehydrogenase (IDH) mutations in gliomas is a powerful example ...
Heterozygous hotspot mutations in isocitrate dehydrogenases (IDH) IDH1 or IDH2 are frequently observ...
Heterozygous hotspot mutations in isocitrate dehydrogenases (IDH) IDH1 or IDH2 are frequently observ...
-dependent isocitrate dehydrogenase (IDH2). Several different amino acid substitutions recur at eith...