The regulation of many targets of the Wnt/β-catenin signaling pathway is thought to occur through a transcriptional switch that is achieved by β-catenin binding to TCF transcription factors. Recent work indicates that β-catenin's intrinsic affinity for TCF is not sufficient for the switch to occur
In recent years,Wnt/β-catenin signaling has been identified as a key player in embryogene-sis and hu...
The SOX family of transcription factors have emerged as modulators of canonical Wnt/β-catenin signal...
The canonical Wnt pathway has gathered much attention in recent years owing to its fundamental contr...
SummaryWnt signaling regulates virtually every cell fate decision during development. How can the sa...
β-Catenin plays a dual role as an adhesion molecule in adherens junctions at the plasma membrane and...
Active canonical Wnt signaling results in recruitment of β-catenin to DNA by TCF/LEF family members,...
Wnt/β-catenin signal transduction requires direct binding of β-catenin to Tcf/Lef proteins, an event...
The wnt signal transduction pathway is involved in many differentiation events during embryonic deve...
The Wnt/β-catenin signaling pathway is crucially involved in embryonic development, stem cell mainte...
In contrast to non-canonical ligands, canonical Wnts promote the stabilization of β-catenin, which i...
Wnt signaling stabilizes -catenin, which binds to TCF/LEF proteins, converting them from transcripti...
The canonical Wnt signaling pathway (or Wnt/β-catenin pathway) plays a pivotal role in embryonic dev...
Cells have developed numerous adaptation mechanisms to external cues by controlling signaling-pathwa...
<p>In the absence of the Wnt ligand, Arm/ β-catenin (β) is phosphorylated by a complex of Axin, APC,...
SummaryTranscription factors of the TCF family are key mediators of the Wnt/β-catenin pathway. TCF u...
In recent years,Wnt/β-catenin signaling has been identified as a key player in embryogene-sis and hu...
The SOX family of transcription factors have emerged as modulators of canonical Wnt/β-catenin signal...
The canonical Wnt pathway has gathered much attention in recent years owing to its fundamental contr...
SummaryWnt signaling regulates virtually every cell fate decision during development. How can the sa...
β-Catenin plays a dual role as an adhesion molecule in adherens junctions at the plasma membrane and...
Active canonical Wnt signaling results in recruitment of β-catenin to DNA by TCF/LEF family members,...
Wnt/β-catenin signal transduction requires direct binding of β-catenin to Tcf/Lef proteins, an event...
The wnt signal transduction pathway is involved in many differentiation events during embryonic deve...
The Wnt/β-catenin signaling pathway is crucially involved in embryonic development, stem cell mainte...
In contrast to non-canonical ligands, canonical Wnts promote the stabilization of β-catenin, which i...
Wnt signaling stabilizes -catenin, which binds to TCF/LEF proteins, converting them from transcripti...
The canonical Wnt signaling pathway (or Wnt/β-catenin pathway) plays a pivotal role in embryonic dev...
Cells have developed numerous adaptation mechanisms to external cues by controlling signaling-pathwa...
<p>In the absence of the Wnt ligand, Arm/ β-catenin (β) is phosphorylated by a complex of Axin, APC,...
SummaryTranscription factors of the TCF family are key mediators of the Wnt/β-catenin pathway. TCF u...
In recent years,Wnt/β-catenin signaling has been identified as a key player in embryogene-sis and hu...
The SOX family of transcription factors have emerged as modulators of canonical Wnt/β-catenin signal...
The canonical Wnt pathway has gathered much attention in recent years owing to its fundamental contr...