CpG methylation of DNA silences TLR9-mediated innate immune recognition. In this issue of Immunity, Kariko et al. (2005) suggest that the innate immune recognition of RNA by TLR3, TLR7, or TLR8 is in fact controlled by modification of nucleotides, including methylation
ABSTRACT Invading pathogen nucleic acids are recognized and bound by cytoplasmic (retinoic acid-indu...
Although it is well documented that the immunological activity of cytosine–guanine (CpG) motifs is a...
Cellular recognition of pathogen DNA is used as a means to signal infection. Toll-like receptor 9 (T...
CpG methylation of DNA silences TLR9-mediated innate immune recognition. In this issue of Immunity, ...
International audienceSensing of nucleic acids for molecular discrimination between self and non-sel...
SummaryDNA and RNA stimulate the mammalian innate immune system through activation of Toll-like rece...
TLR7 and TLR8 recognize RNA from pathogens and lead to subsequent immune stimulation. Here we demons...
The Toll-like receptor 9 (TLR9) is activated by DNA presented in acidified, intracellular compartmen...
Bacterial and viral RNA are potent stimulators of the innate immune system, leading to im-mune cell ...
When a pathogen attacks, the immune system rapidly mobilizes host defenses in order to reduce the mi...
Toll-like receptors (TLRs) are a family of pat-tern recognition receptors that have evolved to detec...
AbstractThe Regulation of TLR7 and TLR9 in the Prevention of AutoimmunityByZachary Robert NewmanDoct...
Copyright © 2013 István Fűri et al. This is an open access article distributed under the Creative ...
Toll-like receptors are a family of pattern recognition receptors (PRRs), which have evolved to reco...
RNA is subject to a wide array of post-transcriptional modifications. 2'-O-methylation is an essenti...
ABSTRACT Invading pathogen nucleic acids are recognized and bound by cytoplasmic (retinoic acid-indu...
Although it is well documented that the immunological activity of cytosine–guanine (CpG) motifs is a...
Cellular recognition of pathogen DNA is used as a means to signal infection. Toll-like receptor 9 (T...
CpG methylation of DNA silences TLR9-mediated innate immune recognition. In this issue of Immunity, ...
International audienceSensing of nucleic acids for molecular discrimination between self and non-sel...
SummaryDNA and RNA stimulate the mammalian innate immune system through activation of Toll-like rece...
TLR7 and TLR8 recognize RNA from pathogens and lead to subsequent immune stimulation. Here we demons...
The Toll-like receptor 9 (TLR9) is activated by DNA presented in acidified, intracellular compartmen...
Bacterial and viral RNA are potent stimulators of the innate immune system, leading to im-mune cell ...
When a pathogen attacks, the immune system rapidly mobilizes host defenses in order to reduce the mi...
Toll-like receptors (TLRs) are a family of pat-tern recognition receptors that have evolved to detec...
AbstractThe Regulation of TLR7 and TLR9 in the Prevention of AutoimmunityByZachary Robert NewmanDoct...
Copyright © 2013 István Fűri et al. This is an open access article distributed under the Creative ...
Toll-like receptors are a family of pattern recognition receptors (PRRs), which have evolved to reco...
RNA is subject to a wide array of post-transcriptional modifications. 2'-O-methylation is an essenti...
ABSTRACT Invading pathogen nucleic acids are recognized and bound by cytoplasmic (retinoic acid-indu...
Although it is well documented that the immunological activity of cytosine–guanine (CpG) motifs is a...
Cellular recognition of pathogen DNA is used as a means to signal infection. Toll-like receptor 9 (T...
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