AbstractThe aim of the present study was to evaluate a possible interference of a-lipoic acid (LA) or its reduced form (dithiol dihydrolipoic acid = DHLA) in the cardiac ischemia/reperfusion injury both at the level of the intact organ and at the subcellular level of mitochondria. In order to follow the effect of LA on the ischemia/reperfusion injury of the heart the isolated perfused organ was subjected to total global ischemia and reperfusion in the presence and absence of different concentrations of LA. Treatment with 0.5 μM LA improved the recovery of hemodynamic parameters; electrophysiological parameters were not influenced. However, application of 10 μM LA to rat hearts further impaired the recovery of hemodynamic functions and prolo...
International audienceDiabetes has emerged as a major threat to worldwide health. The exact mechanis...
The effect of alpha-lipoic acid (LA) on the cardiotoxicity induced by doxorubicin (DOX) was investig...
The effect of alpha-lipoic acid (LA) on the cardiotoxicity induced by doxorubicin (DOX) was investig...
AbstractThe aim of the present study was to evaluate a possible interference of a-lipoic acid (LA) o...
International audienceThe aim of our work was to study (1) the antioxidant properties of lipoic acid...
The present study investigates the effects and mechanisms of α-Lipoic acid (LA) on myocardial infarc...
The present study investigates the effects and mechanisms of α-Lipoic acid (LA) on myocardial infarc...
Alpha-lipoic acid (α-LA) is a disulfide compound and one of the most effective antioxidants. Many st...
Using Langendorff method, isolated mouse heart was perfused with Krebs-Hensleit (KH) buffer solution...
Background and Objectives: Reactive oxygen species (ROS) and mitogen-activated protein (MAP) kinase ...
Ischemic-reperfusion injury in humans occurs in conditions such as stroke, cardiac arrest, subarachn...
Isolated rat hearts were subjected to increasing periods of ischemia and reperfusion for examining t...
There is strong accumulating evidence that a a-lipoic acid (LA) supplement is good insurance, and wo...
Cardiac ischemia/reperfusion injury is associated with the formation and action of lipid mediators d...
α-Lipoic acid (LA) has been shown to improve the diabetic cardiac symptoms. However, the underlying ...
International audienceDiabetes has emerged as a major threat to worldwide health. The exact mechanis...
The effect of alpha-lipoic acid (LA) on the cardiotoxicity induced by doxorubicin (DOX) was investig...
The effect of alpha-lipoic acid (LA) on the cardiotoxicity induced by doxorubicin (DOX) was investig...
AbstractThe aim of the present study was to evaluate a possible interference of a-lipoic acid (LA) o...
International audienceThe aim of our work was to study (1) the antioxidant properties of lipoic acid...
The present study investigates the effects and mechanisms of α-Lipoic acid (LA) on myocardial infarc...
The present study investigates the effects and mechanisms of α-Lipoic acid (LA) on myocardial infarc...
Alpha-lipoic acid (α-LA) is a disulfide compound and one of the most effective antioxidants. Many st...
Using Langendorff method, isolated mouse heart was perfused with Krebs-Hensleit (KH) buffer solution...
Background and Objectives: Reactive oxygen species (ROS) and mitogen-activated protein (MAP) kinase ...
Ischemic-reperfusion injury in humans occurs in conditions such as stroke, cardiac arrest, subarachn...
Isolated rat hearts were subjected to increasing periods of ischemia and reperfusion for examining t...
There is strong accumulating evidence that a a-lipoic acid (LA) supplement is good insurance, and wo...
Cardiac ischemia/reperfusion injury is associated with the formation and action of lipid mediators d...
α-Lipoic acid (LA) has been shown to improve the diabetic cardiac symptoms. However, the underlying ...
International audienceDiabetes has emerged as a major threat to worldwide health. The exact mechanis...
The effect of alpha-lipoic acid (LA) on the cardiotoxicity induced by doxorubicin (DOX) was investig...
The effect of alpha-lipoic acid (LA) on the cardiotoxicity induced by doxorubicin (DOX) was investig...