AbstractTumor cell dissemination to distant organ sites is a complex process involving multiple cell types, soluble growth factors, adhesion receptors, and tissue remodeling. A new study in this issue of Cancer Cell shows that MMP9-expressing tumor-associated macrophages play a key role in prepping premetastatic sites for eventual malignant cell growth in a manner dependent upon vascular endothelial growth factor receptor-1 (VEGFR-1)
Tumor cells communicate with the cells of their microenvironment via a series of molecular and cellu...
Cancer is a major public health problem with breast cancer being among the leading causes of cancer ...
AbstractAccording to established notion, one of the major angiogenesis-inducing factors, pro-matrix ...
Item does not contain fulltextTumor cell dissemination to distant organ sites is a complex process i...
AbstractTumor cell dissemination to distant organ sites is a complex process involving multiple cell...
AbstractThe molecular mechanism of tissue-specific metastasis in tumors endogenously expressing memb...
Metastasis, the main cause of cancer-related death, has traditionally been viewed as a late-occurrin...
Having the capability to proteolyze diverse structural and signaling proteins, matrix metalloprotein...
Chinese Ministry of Science and Technology [2009CB522205]; Chinese High Technology Research and Deve...
BACKGROUND: The current paradigm suggests that matrix metalloproteinase 9 (MMP-9) expressed by strom...
Oral squamous cell carcinoma (OSCC) is one of the most common types of cancers in developing countri...
Fibroblast growth factors 9 (FGF9) modulates cell proliferation, differentiation and motility for de...
Members of matrix metalloproteinase (MMP) family promote cancer cell migration, invasion, and metast...
Abstract. Macrophages constitute a large proportion of the immune cell infiltrate, which is present ...
Lung cancer, including carcinogenesis and therapy, is one of the main research focuses today. One of...
Tumor cells communicate with the cells of their microenvironment via a series of molecular and cellu...
Cancer is a major public health problem with breast cancer being among the leading causes of cancer ...
AbstractAccording to established notion, one of the major angiogenesis-inducing factors, pro-matrix ...
Item does not contain fulltextTumor cell dissemination to distant organ sites is a complex process i...
AbstractTumor cell dissemination to distant organ sites is a complex process involving multiple cell...
AbstractThe molecular mechanism of tissue-specific metastasis in tumors endogenously expressing memb...
Metastasis, the main cause of cancer-related death, has traditionally been viewed as a late-occurrin...
Having the capability to proteolyze diverse structural and signaling proteins, matrix metalloprotein...
Chinese Ministry of Science and Technology [2009CB522205]; Chinese High Technology Research and Deve...
BACKGROUND: The current paradigm suggests that matrix metalloproteinase 9 (MMP-9) expressed by strom...
Oral squamous cell carcinoma (OSCC) is one of the most common types of cancers in developing countri...
Fibroblast growth factors 9 (FGF9) modulates cell proliferation, differentiation and motility for de...
Members of matrix metalloproteinase (MMP) family promote cancer cell migration, invasion, and metast...
Abstract. Macrophages constitute a large proportion of the immune cell infiltrate, which is present ...
Lung cancer, including carcinogenesis and therapy, is one of the main research focuses today. One of...
Tumor cells communicate with the cells of their microenvironment via a series of molecular and cellu...
Cancer is a major public health problem with breast cancer being among the leading causes of cancer ...
AbstractAccording to established notion, one of the major angiogenesis-inducing factors, pro-matrix ...