ObjectivesThe aim of this study was to investigate the effect of simvastatin and ezetimibe on inflammation, disease activity, endothelial dysfunction, and arterial stiffness in a cohort of rheumatoid arthritis (RA) patients.BackgroundRheumatoid arthritis is a chronic inflammatory condition associated with increased cardiovascular risk. Statins reduce inflammation and disease activity in RA patients, but whether this is due to pleiotropism or cholesterol lowering per se is unclear.MethodsTwenty patients received 20 mg simvastatin or 10 mg ezetimibe each for 6 weeks in a randomized double-blind crossover study. Disease activity, blood pressure, aortic pulse wave velocity (PWV), brachial artery flow-mediated dilation (FMD), and serum inflammat...
Objectives. Systemic inflammation may play an important role in the accelerated atherosclerosis and ...
Background/Aim: Statin treatment improves endothelial function. It is matter of debate, however, if ...
Background—By inhibiting 3-hydroxy-3-methylglutaryl coenzyme A reductase, statins not only reduce ch...
Background: Chronic systemic inflammation may contribute to accelerated atherosclerosis and increase...
ObjectivesThe aim of this study was to investigate the effect of simvastatin and ezetimibe on inflam...
Objective. To investigate the effects of angiotensin-converting enzyme (ACE) inhibitors and statins ...
Background: Rheumatoid arthritis (RA) is a chronic inflammatory joint disorder with unknown etiology...
<p><strong>Objective:</strong> to evaluate the basic and pleiotropic effects of atorvastatin in pati...
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Both acute and chronic inflammation are associated wit...
Introduction Endothelial dysfunction is an early step in the atherosclerotic process...
Abstract Background: The effect of statins on the endothelial function in humans remains under disc...
Abstract Background: The effect of statins on the endothelial function in humans remains under disc...
Rheumatoid arthritis (RA) is an autoimmune, inflammatory disorder associated with excess cardiovascu...
Sylvain Mathieu,1,2 Marion Couderc,1,2 Baptiste Glace,1,2 Bruno Pereira,2,3 Anne Tournadre,1,2 Jean-...
BACKGROUND: Rheumatoid arthritis is characterised by inflammatory synovitis, articular destruction, ...
Objectives. Systemic inflammation may play an important role in the accelerated atherosclerosis and ...
Background/Aim: Statin treatment improves endothelial function. It is matter of debate, however, if ...
Background—By inhibiting 3-hydroxy-3-methylglutaryl coenzyme A reductase, statins not only reduce ch...
Background: Chronic systemic inflammation may contribute to accelerated atherosclerosis and increase...
ObjectivesThe aim of this study was to investigate the effect of simvastatin and ezetimibe on inflam...
Objective. To investigate the effects of angiotensin-converting enzyme (ACE) inhibitors and statins ...
Background: Rheumatoid arthritis (RA) is a chronic inflammatory joint disorder with unknown etiology...
<p><strong>Objective:</strong> to evaluate the basic and pleiotropic effects of atorvastatin in pati...
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Both acute and chronic inflammation are associated wit...
Introduction Endothelial dysfunction is an early step in the atherosclerotic process...
Abstract Background: The effect of statins on the endothelial function in humans remains under disc...
Abstract Background: The effect of statins on the endothelial function in humans remains under disc...
Rheumatoid arthritis (RA) is an autoimmune, inflammatory disorder associated with excess cardiovascu...
Sylvain Mathieu,1,2 Marion Couderc,1,2 Baptiste Glace,1,2 Bruno Pereira,2,3 Anne Tournadre,1,2 Jean-...
BACKGROUND: Rheumatoid arthritis is characterised by inflammatory synovitis, articular destruction, ...
Objectives. Systemic inflammation may play an important role in the accelerated atherosclerosis and ...
Background/Aim: Statin treatment improves endothelial function. It is matter of debate, however, if ...
Background—By inhibiting 3-hydroxy-3-methylglutaryl coenzyme A reductase, statins not only reduce ch...