The B cell receptor (BCR) activates the ERK kinases, but what does ERK do? In this issue of Immunity, Yasuda et al. (2008) show that ERK controls a transcription factor network by which the pre-BCR drives early B cell development
textabstractSignalling from the BCR or its immature form, the pre-BCR, was shown to be crucial for B...
The B cell receptor (BCR) is a major regulator of B cell development, activation, and cell death. Th...
Cross-linking of the B cell receptor (BCR) on the immature B lymphoma cell line BKS-2 induces growth...
The B cell receptor (BCR) activates the ERK kinases, but what does ERK do? In this issue of Immunity...
SummaryThe pre-B cell receptor (pre-BCR) plays a crucial role in the development of immature B cells...
The pre-B cell receptor (pre-BCR) plays a crucial role in the development of immature B cells. Altho...
The immune synapse (IS) is a special polarized structure that optimizes the functions of the B cell ...
Early B-cell development is an ordered and highly regulated process with alternating phases of cell ...
Newly generated bone marrow B cells are positively selected into the peripheral lymphoid tissue only...
SummaryOCA-B was originally identified as a nuclear transcriptional coactivator that is essential fo...
The extracellular signal-regulated kinase (ERK) pathway plays an important role during the developme...
AbstractB lymphocyte development is regulated at multiple checkpoints, mediated by signals originati...
The number of mature B cells is carefully controlled by signalling from receptors that support B cel...
SummaryActivation of extracellular-signal-regulated protein kinase (Erk) is central to growth-factor...
Engagement of B cell receptors evokes a cascade of signaling events leading to clonal expansion, dif...
textabstractSignalling from the BCR or its immature form, the pre-BCR, was shown to be crucial for B...
The B cell receptor (BCR) is a major regulator of B cell development, activation, and cell death. Th...
Cross-linking of the B cell receptor (BCR) on the immature B lymphoma cell line BKS-2 induces growth...
The B cell receptor (BCR) activates the ERK kinases, but what does ERK do? In this issue of Immunity...
SummaryThe pre-B cell receptor (pre-BCR) plays a crucial role in the development of immature B cells...
The pre-B cell receptor (pre-BCR) plays a crucial role in the development of immature B cells. Altho...
The immune synapse (IS) is a special polarized structure that optimizes the functions of the B cell ...
Early B-cell development is an ordered and highly regulated process with alternating phases of cell ...
Newly generated bone marrow B cells are positively selected into the peripheral lymphoid tissue only...
SummaryOCA-B was originally identified as a nuclear transcriptional coactivator that is essential fo...
The extracellular signal-regulated kinase (ERK) pathway plays an important role during the developme...
AbstractB lymphocyte development is regulated at multiple checkpoints, mediated by signals originati...
The number of mature B cells is carefully controlled by signalling from receptors that support B cel...
SummaryActivation of extracellular-signal-regulated protein kinase (Erk) is central to growth-factor...
Engagement of B cell receptors evokes a cascade of signaling events leading to clonal expansion, dif...
textabstractSignalling from the BCR or its immature form, the pre-BCR, was shown to be crucial for B...
The B cell receptor (BCR) is a major regulator of B cell development, activation, and cell death. Th...
Cross-linking of the B cell receptor (BCR) on the immature B lymphoma cell line BKS-2 induces growth...