C4. Pneumonia adquirida na comunidade (PAC): estudo retrospectivo num hospital central

CAP is an important cause of morbidity and mortality in hospitalized patients. The aim of this study was to analyze etiology, risk factors, treatment and mortality of CAP. We conducted a retrospective analysis of clinical data from 246 patients admitted to our Department with CAP diagnosis throughout an 24 month period.The patients were in average age 58,9 years old and 61% were male. In 48,6% significant co-morbidities were found. On chest X-ray there was a multilobar involvement in 17,1% of the cases, an alveolar pattern in 66,7% and pleural effusion in 18,3%.Etiologic agents were investigated in 195 of the cases (75,9%) and a positive identification was made in 57 (29,2%) of them: 11% blood cultures (19/173), 30% sputum cultures (48/160) and 10,4% serologic examinations and urine antigen testing for Legionella (7/67). The most commonly isolated bacteria were S. pneumoniae (47%), Gram-negatives (26%) and H. influenza (18%).Amoxicillin/clavulanate (82,9%) and macrolides (68,1%) were the most used antibiotics. An association of antibiotics was elected to 61,6% of the patients. During treatment was in average 12 days. A positive response to treatment was obtained in 93% patients. The mortality rate was 5,1%.S. pneumoniae was the most common single agent causing CAP. Choice of were in agreement with international guidelines criteria produced a positive response, as judged by a low mortality rate