AbstractThe Arf tumor suppressor is a key component of the p53 tumor surveillance pathway, and its expression is activated by abnormal proliferation signals. In a recent paper, Lees and coworkers investigate the regulation of Arf expression by E2Fs and demonstrate that in normal cells E2F3 is a pivotal repressor of Arf
Using alternative reading frames, the human ARF-INK4a locus en-codes two unrelated proteins that bot...
Item does not contain fulltextThe p16(INK4a)/pRB/E2F and p19(ARF)/p53 tumor suppressor pathways are ...
Summary: The ARF and p53 tumor suppressors are thought to act in a linear pathway to prevent cellula...
AbstractThe Arf tumor suppressor is a key component of the p53 tumor surveillance pathway, and its e...
International audienceThe INK4a/ARF locus which is frequently inactivated in human tumours encodes t...
Effective tumor suppression requires the appropriate function of two major signaling pathways, the p...
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2007.Vita.Includes bibliog...
The ARF/MDM2/p53 pathway is a principal defense mechanism to protect the organism from uncontrolled ...
The ARF protein is a key mediator of the activation of the p53 tumor suppressor in response to exces...
Contains fulltext : 112855.pdf (publisher's version ) (Closed access
p14/p19ARF (ARF) is a tumor suppressor gene that is frequently mutated in human cancer. ARF has mult...
The tumour suppressor ARF is specifically required for p53 activation under oncogenic stress(1-6). R...
Members of the E2F family of transcription factors play an important role in regulating the cell cyc...
Loss of the regulatory networks that monitor cellular growth and proliferation is among the cascade ...
AbstractThe E2F family of transcription factors plays a pivotal role in the regulation of cell proli...
Using alternative reading frames, the human ARF-INK4a locus en-codes two unrelated proteins that bot...
Item does not contain fulltextThe p16(INK4a)/pRB/E2F and p19(ARF)/p53 tumor suppressor pathways are ...
Summary: The ARF and p53 tumor suppressors are thought to act in a linear pathway to prevent cellula...
AbstractThe Arf tumor suppressor is a key component of the p53 tumor surveillance pathway, and its e...
International audienceThe INK4a/ARF locus which is frequently inactivated in human tumours encodes t...
Effective tumor suppression requires the appropriate function of two major signaling pathways, the p...
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2007.Vita.Includes bibliog...
The ARF/MDM2/p53 pathway is a principal defense mechanism to protect the organism from uncontrolled ...
The ARF protein is a key mediator of the activation of the p53 tumor suppressor in response to exces...
Contains fulltext : 112855.pdf (publisher's version ) (Closed access
p14/p19ARF (ARF) is a tumor suppressor gene that is frequently mutated in human cancer. ARF has mult...
The tumour suppressor ARF is specifically required for p53 activation under oncogenic stress(1-6). R...
Members of the E2F family of transcription factors play an important role in regulating the cell cyc...
Loss of the regulatory networks that monitor cellular growth and proliferation is among the cascade ...
AbstractThe E2F family of transcription factors plays a pivotal role in the regulation of cell proli...
Using alternative reading frames, the human ARF-INK4a locus en-codes two unrelated proteins that bot...
Item does not contain fulltextThe p16(INK4a)/pRB/E2F and p19(ARF)/p53 tumor suppressor pathways are ...
Summary: The ARF and p53 tumor suppressors are thought to act in a linear pathway to prevent cellula...
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