Effects of a Sustained Inflation in Preterm Infants at Birth

van Vonderen, Jeroen J.
Hooper, Stuart B.
Hummler, Helmut D.
Lopriore, Enrico
te Pas, Arjan B.

Open link

Publication date

November 2014

DOI

10.1016/j.jpeds.2014.06.007

Publisher

Elsevier Inc.

Abstract

ObjectiveTo assess the clinical effect of an initial sustained inflation of 10 seconds and 25 cmH2O in preterm infants at birth.Study designIn this observational study inflation pressures and tidal volumes were recorded with the use of respiratory function monitoring of preterm infants <32 weeks' gestation receiving a sustained inflation. Inspiratory tidal volume (Vti) and expiratory tidal volume (Vte) of sustained inflation and cumulative Vti and Vte of breaths during sustained inflation were determined. Heart rate and oxygen saturation were measured before and after the sustained inflation.ResultsSeventy infants were included (median [IQR]: gestational age 29 [27-30] weeks). Mean (SD) sustained inflation duration was 10.5 seconds (2.9 sec...