In this issue of Cancer Cell, Zhao and colleagues test various chimeric antigen receptor (CAR) T cells to show that CD28-CD3ζ CAR T cells that constitutively express 4-1BBL promote T cell expansion and tumor eradication while reducing exhaustion. The results have important implications for the development of effective CAR T cell therapies in cancer patients
One important purpose of T cell engineering is to generate tumor-targeted T cells through the geneti...
Abstract As chimeric antigen receptor (CAR) T cells have displayed an unprecedented efficacy in the ...
CAR-T cell therapy has emerged as a promising cancer treatment modality with curative potential. In ...
In this issue of Cancer Cell, Zhao and colleagues test various chimeric antigen receptor (CAR) T cel...
In this issue of Cancer Cell, Zhao and colleagues test various chimeric antigen receptor (CAR) T cel...
Chimeric antigen receptor (CAR) is generated by fusing a cancer-specific antibody’s antigen recognit...
Chimeric antigen receptor (CAR) therapy is based on patient blood-derived T cells and natural killer...
Abstract Harnessing the power of the immune system to target cancer has long been a goal of tumor im...
Chimeric antigen receptor (CAR)-T cell therapy represents one of the most innovative immunotherapy a...
BACKGROUND: Current cancer drugs and treatments are aiming at eradicating tumor cells, but often are...
Cancer therapy has entered a new era, transitioning from unspecific chemotherapeutic agents to incre...
Abstract Adoptive cell therapy using chimeric antigen receptor (CAR)-engineered T cells has emerged ...
The immune system acting via cancer immune-surveillance is considered a potential target for improvi...
In the past decade, chimeric antigen receptor (CAR) T cell technology has revolutionized cancer immu...
T cells engineered to express chimeric antigen receptors (CARs) specific for CD19 have yielded remar...
One important purpose of T cell engineering is to generate tumor-targeted T cells through the geneti...
Abstract As chimeric antigen receptor (CAR) T cells have displayed an unprecedented efficacy in the ...
CAR-T cell therapy has emerged as a promising cancer treatment modality with curative potential. In ...
In this issue of Cancer Cell, Zhao and colleagues test various chimeric antigen receptor (CAR) T cel...
In this issue of Cancer Cell, Zhao and colleagues test various chimeric antigen receptor (CAR) T cel...
Chimeric antigen receptor (CAR) is generated by fusing a cancer-specific antibody’s antigen recognit...
Chimeric antigen receptor (CAR) therapy is based on patient blood-derived T cells and natural killer...
Abstract Harnessing the power of the immune system to target cancer has long been a goal of tumor im...
Chimeric antigen receptor (CAR)-T cell therapy represents one of the most innovative immunotherapy a...
BACKGROUND: Current cancer drugs and treatments are aiming at eradicating tumor cells, but often are...
Cancer therapy has entered a new era, transitioning from unspecific chemotherapeutic agents to incre...
Abstract Adoptive cell therapy using chimeric antigen receptor (CAR)-engineered T cells has emerged ...
The immune system acting via cancer immune-surveillance is considered a potential target for improvi...
In the past decade, chimeric antigen receptor (CAR) T cell technology has revolutionized cancer immu...
T cells engineered to express chimeric antigen receptors (CARs) specific for CD19 have yielded remar...
One important purpose of T cell engineering is to generate tumor-targeted T cells through the geneti...
Abstract As chimeric antigen receptor (CAR) T cells have displayed an unprecedented efficacy in the ...
CAR-T cell therapy has emerged as a promising cancer treatment modality with curative potential. In ...
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