Effect of Nanohydroxyapatite Addition on the Pore Morphology and Mechanical Properties of Freeze Cast Hydroxyapatite Scaffolds

AbstractIn current study, the effect of nanohydroxyapatite (nHA) content on microstructural and mechanical properties of hydroxyapatite scaffolds fabricated using the water-based freeze casting method has been investigated. In the experimental procedure, the solidified samples were prepared by hydroxyapatite slurries containing different concentration of nHA followed by sintering procedure at 1350°C. The characteristics of the initial powders, microstructure, and mechanical strength of the scaffolds were assessed by X-ray diffraction, scanning electron microscopy, and mechanical strength test, respectively. The results showed that, increasing of nHA leading to decrease in pore size, increase in inter structural bridges, reduce in porosity and increase in compressive strength of the hydroxyapatite scaffolds, which is believed to be more effective in bone tissue engineering applications