0225: Impaired glucose tolerance and impared fasting glucose in patients with essential hypertension

ObjectiveThe aim of the study was to assess of frequency and overlap of impaired glucose tolerance (IGT) and impaired fasting glucose (IFG) in hyper-tensive patients.Methods81 patients with essential hypertension (47 females and 34 males), from 36 to 65 years old were enrolled in the study. IGT was diagnosed then plasma glucose level after oral intake of 75g of glucose was in the range 7.8-11.1mmol/l, IFG was established then fasting plasma glucose was 6.1–6.9mmol/l.ResultsIFG was found in 18 (22%), IGT – in 40 (49%) of patients. The total number of patients with prediabetes (IFG and/or IGT) was 42 (51%).In 16 cases there was combination of IFG and IGT, in 2 cases – IFG was isolated, in 24 cases – IGT was isolated. Body mass index (BMI) was higher in prediabetic compare to normoglycemic patients (31.3±5.7 versus 28.4±5.1kg/m 2, p=0.017). In this study obesity and overweight were diagnosed in 61 (75%) patients.ConclusionsPrediabetes was found in half of patients with essential hyper-tension and predominantly associated with obesity and overweight. IGT is twice more sensitive marker of prediabetes than IFG