Having the correct number of centrosomes is crucial for proper chromosome segregation during cell division and for the prevention of aneuploidy, a hallmark of many cancer cells. Several recent studies (Basto et al., 2008; Kwon et al., 2008; Yang et al., 2008) reveal the importance of mechanisms that protect against the consequences of harboring too many centrosomes
Centrosomes are microtubule-organizing centers that duplicate in S phase to form bipolar spindles th...
Centrosomes are complex structures, which are embedded into the opposite poles of the mitotic spindl...
Centrosome abnormalities are linked to genomic instability and are considered one possible cause of ...
Having the correct number of centrosomes is crucial for proper chromosome segregation during cell di...
SummaryThe regulation of centrosome number is lost in many tumors and the presence of extra centroso...
The centrosome is the microtubule organizing center important for the establishment of the mitotic s...
Aberrations in the centrosome number and structure can readily be detected at all stages of tumor pr...
Cancer kills one in five people each year in western societies, therefore clinicians are eager to fi...
Contains fulltext : 154730.pdf (publisher's version ) (Closed access)Accurate segr...
The formation of a bipolar mitotic spindle is crucial for the even segregation of genetic material i...
The formation of a bipolar mitotic spindle is crucial for the even segregation of genetic material i...
Centrosome amplification (the presence of more than two centrosomes at mitosis) is characteristic of...
Accurate segregation of duplicated chromosomes between two daughter cells depends on bipolar spindle...
The transformation of a normal cell to a tumor cell is a result of a failure somewhere in a complica...
The formation of a bipolar mitotic spindle is crucial for the even segregation of genetic material i...
Centrosomes are microtubule-organizing centers that duplicate in S phase to form bipolar spindles th...
Centrosomes are complex structures, which are embedded into the opposite poles of the mitotic spindl...
Centrosome abnormalities are linked to genomic instability and are considered one possible cause of ...
Having the correct number of centrosomes is crucial for proper chromosome segregation during cell di...
SummaryThe regulation of centrosome number is lost in many tumors and the presence of extra centroso...
The centrosome is the microtubule organizing center important for the establishment of the mitotic s...
Aberrations in the centrosome number and structure can readily be detected at all stages of tumor pr...
Cancer kills one in five people each year in western societies, therefore clinicians are eager to fi...
Contains fulltext : 154730.pdf (publisher's version ) (Closed access)Accurate segr...
The formation of a bipolar mitotic spindle is crucial for the even segregation of genetic material i...
The formation of a bipolar mitotic spindle is crucial for the even segregation of genetic material i...
Centrosome amplification (the presence of more than two centrosomes at mitosis) is characteristic of...
Accurate segregation of duplicated chromosomes between two daughter cells depends on bipolar spindle...
The transformation of a normal cell to a tumor cell is a result of a failure somewhere in a complica...
The formation of a bipolar mitotic spindle is crucial for the even segregation of genetic material i...
Centrosomes are microtubule-organizing centers that duplicate in S phase to form bipolar spindles th...
Centrosomes are complex structures, which are embedded into the opposite poles of the mitotic spindl...
Centrosome abnormalities are linked to genomic instability and are considered one possible cause of ...
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