The Central Line Associated Blood Stream Infection (CLABSI) is inevitable contributing factor in increased morbidity and mortality of patients admitted to Intensive Care Units (ICU) worldwide resulting in an increased financial cost and prolonged hospital stay (Ascher et al., 2012; Rosenthal et al., 2012).CLABSI prevention strategies are the important part of improving patient safety and quality of care for patient with central venous line in ICU. The Center for Disease Control and Prevention (CDC) and the National Healthcare Safety Network (NHSN) benchmarked acceptable limits and issued recommendation for reduction of CLABSI to minimum.The poster presentation aims to share our experience and challenges that we faced in reducing CLABSI rate...