In this issue, Sorbara et al. (2014) demonstrate that axonal transport impairment is an early feature of neurodegeneration in multiple sclerosis models. This transport deficit is reversible by anti-inflammatory intervention but, if untreated, can contribute to late-stage axonal dystrophy
BACKGROUND: Although in situ pathological studies and in vivo magnetic resonance (MR) investigations...
Multiple Sclerosis (MS) is a major cause of neurological disability, which increases predominantly d...
Objective: Trans-synaptic axonal degeneration is a mechanism by which neurodegeneration can spread f...
textabstractThe transport of mitochondria and other cellular components along the axonal microtubule...
SummaryImpaired axonal transport can contribute to axon degeneration and has been described in many ...
Impaired axonal transport can contribute to axon degeneration and has been described in many neurode...
Adult-onset neurodegenerative diseases (AONDs) comprise a heterogeneous group of neurological disord...
It is well recognized that in end-stage multiple sclerosis (MS) pathology there is axon loss. Since ...
OBJECTIVE: To assess axonal damage and its contribution to disability at different stages of multipl...
Axonal degeneration is a major determinant of permanent neurological impairment during multiple scle...
Adult-onset neurodegenerative diseases (AONDs) comprise a heterogeneous group of neurological disord...
Motor neurons typically have very long axons, and fine-tuning axonal transport is crucial for their ...
Multiple sclerosis is a debilitating disease of the central nervous system that has been characteris...
Many neurodegenerative diseases are characterized by deficiencies in neuronal axonal transport, a pr...
Several recent studies have highlighted the role of axonal transport in the pathogenesis of motor ne...
BACKGROUND: Although in situ pathological studies and in vivo magnetic resonance (MR) investigations...
Multiple Sclerosis (MS) is a major cause of neurological disability, which increases predominantly d...
Objective: Trans-synaptic axonal degeneration is a mechanism by which neurodegeneration can spread f...
textabstractThe transport of mitochondria and other cellular components along the axonal microtubule...
SummaryImpaired axonal transport can contribute to axon degeneration and has been described in many ...
Impaired axonal transport can contribute to axon degeneration and has been described in many neurode...
Adult-onset neurodegenerative diseases (AONDs) comprise a heterogeneous group of neurological disord...
It is well recognized that in end-stage multiple sclerosis (MS) pathology there is axon loss. Since ...
OBJECTIVE: To assess axonal damage and its contribution to disability at different stages of multipl...
Axonal degeneration is a major determinant of permanent neurological impairment during multiple scle...
Adult-onset neurodegenerative diseases (AONDs) comprise a heterogeneous group of neurological disord...
Motor neurons typically have very long axons, and fine-tuning axonal transport is crucial for their ...
Multiple sclerosis is a debilitating disease of the central nervous system that has been characteris...
Many neurodegenerative diseases are characterized by deficiencies in neuronal axonal transport, a pr...
Several recent studies have highlighted the role of axonal transport in the pathogenesis of motor ne...
BACKGROUND: Although in situ pathological studies and in vivo magnetic resonance (MR) investigations...
Multiple Sclerosis (MS) is a major cause of neurological disability, which increases predominantly d...
Objective: Trans-synaptic axonal degeneration is a mechanism by which neurodegeneration can spread f...
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