Cancer's Epigenome

Large-scale cancer genomics projects are just starting to trickle into the literature, and the flow will only grow in size and impact in the upcoming year. Nevertheless, the studies so far are already reshaping our view of tumor progression, especially in terms of how cancer manipulates the epigenome for fast growth and adaptability. This Select discusses recent genomics articles that, collectively, offer a new mechanism for cancer evolution and highlight the rising importance of chromatin remodeling factors in cancer