The mechanisms by which p53 suppresses tumor growth remain ill defined. In this issue of Cell Reports, Timofeev et al. (2013) and Valente et al. (2013) reveal context-dependent contributions of p53-dependent apoptosis to its tumor-suppressive function
Tumor suppression by p53 is deficient in the majority of human cancers. Previous studies have sugges...
Copyright © 2012 Razmik Mirzayans et al. This is an open access article distributed under the Creati...
p53 is a transcription factor known to induce apoptosis via transactivating the expression of pro-ap...
The mechanisms by which p53 suppresses tumor growth remain ill defined. In this issue of Cell Report...
The p53 tumor suppressor protein acts as a major defense against cancer. Among its most distinctive ...
The p53 tumor suppressor acts to integrate multiple stress signals into a series of diverse antiprol...
p53 is a key tumor suppressor protein that has numerous functions. Its primary mode of action has ge...
Our genomes are subject to potentially deleterious alterations resulting from endogenous sources (e....
The high frequency of p53 mutation in human cancers indicates the important role of p53 in suppressi...
SummaryThe p53 tumor suppressor governs multiple cell-intrinsic programs, including cell-cycle arres...
The TP53 tumor suppressor is the most frequently mutated gene in human cancer. p53 suppresses tumori...
Activation of the tumour suppressor p53 upon cellular stress can induce a number of different cellul...
p53 has been studied intensively as a major tumour suppressor that detects oncogenic events in cance...
The tumor suppressor p53 regulates different cellular pathways involved in cell survival, DNA repair...
p53 is frequently mutated in cancer and as a result is one of the most intensely studied tumour supp...
Tumor suppression by p53 is deficient in the majority of human cancers. Previous studies have sugges...
Copyright © 2012 Razmik Mirzayans et al. This is an open access article distributed under the Creati...
p53 is a transcription factor known to induce apoptosis via transactivating the expression of pro-ap...
The mechanisms by which p53 suppresses tumor growth remain ill defined. In this issue of Cell Report...
The p53 tumor suppressor protein acts as a major defense against cancer. Among its most distinctive ...
The p53 tumor suppressor acts to integrate multiple stress signals into a series of diverse antiprol...
p53 is a key tumor suppressor protein that has numerous functions. Its primary mode of action has ge...
Our genomes are subject to potentially deleterious alterations resulting from endogenous sources (e....
The high frequency of p53 mutation in human cancers indicates the important role of p53 in suppressi...
SummaryThe p53 tumor suppressor governs multiple cell-intrinsic programs, including cell-cycle arres...
The TP53 tumor suppressor is the most frequently mutated gene in human cancer. p53 suppresses tumori...
Activation of the tumour suppressor p53 upon cellular stress can induce a number of different cellul...
p53 has been studied intensively as a major tumour suppressor that detects oncogenic events in cance...
The tumor suppressor p53 regulates different cellular pathways involved in cell survival, DNA repair...
p53 is frequently mutated in cancer and as a result is one of the most intensely studied tumour supp...
Tumor suppression by p53 is deficient in the majority of human cancers. Previous studies have sugges...
Copyright © 2012 Razmik Mirzayans et al. This is an open access article distributed under the Creati...
p53 is a transcription factor known to induce apoptosis via transactivating the expression of pro-ap...
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