Cellular senescence, a state of irreversible growth arrest, can be triggered by multiple mechanisms including telomere shortening, the epigenetic derepression of the INK4a/ARF locus, and DNA damage. Together these mechanisms limit excessive or aberrant cellular proliferation, and so the state of senescence protects against the development of cancer. Recent evidence suggests that cellular senescence also may be involved in aging
Cellular senescence has historically been viewed as an irreversible cell-cycle arrest mechanism that...
Cellular senescence is a biological phenomenon that has received many interpretations since its orig...
Cellular senescence is a tumor-suppressor mechanism that has been shown to occur in response to mult...
Cellular senescence, a state of irreversible growth arrest, can be triggered by multiple mechanisms ...
Abstract How much do we know about the biology of aging from cell culture studies Most normal somati...
Cellular senescence is eminently characterized by a permanent cell cycle arrest and the acquisition ...
Cellular senescence is a permanent state of cell cycle arrest that occurs in proliferating cells sub...
Cellular senescence is a state of irreversible cell cycle arrest in response to several stressors, i...
Cellular senescence is a permanent state of cell cycle arrest that occurs in proliferating cells sub...
Cell senescence is an irreversible state in which the cell cycle ends. The cell remains metabolicall...
Cellular senescence is a state of irreversible growth arrest activated by a complex response to stre...
Cellular senescence describes an irreversible growth arrest characterized by distinct morphology, ge...
Cellular senescence, a permanent cell cycle arrest, is considered a safeguard mechanism that may pre...
<p>Cellular senescence can be induced by various triggers, including, but not limited to, telomere d...
International audienceCellular senescence entails a state of an essentially irreversible proliferati...
Cellular senescence has historically been viewed as an irreversible cell-cycle arrest mechanism that...
Cellular senescence is a biological phenomenon that has received many interpretations since its orig...
Cellular senescence is a tumor-suppressor mechanism that has been shown to occur in response to mult...
Cellular senescence, a state of irreversible growth arrest, can be triggered by multiple mechanisms ...
Abstract How much do we know about the biology of aging from cell culture studies Most normal somati...
Cellular senescence is eminently characterized by a permanent cell cycle arrest and the acquisition ...
Cellular senescence is a permanent state of cell cycle arrest that occurs in proliferating cells sub...
Cellular senescence is a state of irreversible cell cycle arrest in response to several stressors, i...
Cellular senescence is a permanent state of cell cycle arrest that occurs in proliferating cells sub...
Cell senescence is an irreversible state in which the cell cycle ends. The cell remains metabolicall...
Cellular senescence is a state of irreversible growth arrest activated by a complex response to stre...
Cellular senescence describes an irreversible growth arrest characterized by distinct morphology, ge...
Cellular senescence, a permanent cell cycle arrest, is considered a safeguard mechanism that may pre...
<p>Cellular senescence can be induced by various triggers, including, but not limited to, telomere d...
International audienceCellular senescence entails a state of an essentially irreversible proliferati...
Cellular senescence has historically been viewed as an irreversible cell-cycle arrest mechanism that...
Cellular senescence is a biological phenomenon that has received many interpretations since its orig...
Cellular senescence is a tumor-suppressor mechanism that has been shown to occur in response to mult...
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