AbstractMiller et al. (this issue of Neuron) report that deletion of the 3′UTR of α-CaMKII mRNA prevents dendritic delivery of the mRNA in transgenic mice and thus local synthesis of α-CaMKII protein in dendrites. 3′UTR mutant mice exhibit decreases in α-CaMKII protein in postsynaptic densities, and deficits in late phase LTP and in memory consolidation
CPEB is a sequence-specific RNA binding protein that regulates translation at synapses. In neurons o...
In neurons, the proteins derived from mRNAs localized in dendrites have been implicated in synaptic ...
Regulation of mRNA localization is a conserved cellular process observed in many types of cells and ...
AbstractMiller et al. (this issue of Neuron) report that deletion of the 3′UTR of α-CaMKII mRNA prev...
Local protein synthesis in dendrites contributes to the synaptic modifications underlying learning a...
International audienceLocal protein synthesis in dendrites contributes to the synaptic modifications...
<p><b>A, </b><i>In situ</i> hybridization for CaMKIIα mRNA in wild-type mice (WT, upper panels) and ...
Most mammalian dendrites have surprisingly few copy numbers of mRNAs relative to the large number of...
In a neuron's dendritic spine, the location of CaMKII is controlled by a number of interacting facto...
In a neuron's dendritic spine, the location of CaMKII is controlled by a number of interacting facto...
<p><b>A,B </b><i>In situ</i> hybridization for CaMKIIα mRNA. <b>A,</b> On a horizontal section, CaMK...
uni-muenchen.de It is widely believed that activity-dependent synaptic plasticity is the basis for l...
In a neuron's dendritic spine, the location of CaMKII is controlled by a number of interacting facto...
Activity-dependent and synapse-specific translation of mRNAs is required for long-term changes in sy...
Synaptic transmission in neurons is a measure of communication at synapses, the points of contact be...
CPEB is a sequence-specific RNA binding protein that regulates translation at synapses. In neurons o...
In neurons, the proteins derived from mRNAs localized in dendrites have been implicated in synaptic ...
Regulation of mRNA localization is a conserved cellular process observed in many types of cells and ...
AbstractMiller et al. (this issue of Neuron) report that deletion of the 3′UTR of α-CaMKII mRNA prev...
Local protein synthesis in dendrites contributes to the synaptic modifications underlying learning a...
International audienceLocal protein synthesis in dendrites contributes to the synaptic modifications...
<p><b>A, </b><i>In situ</i> hybridization for CaMKIIα mRNA in wild-type mice (WT, upper panels) and ...
Most mammalian dendrites have surprisingly few copy numbers of mRNAs relative to the large number of...
In a neuron's dendritic spine, the location of CaMKII is controlled by a number of interacting facto...
In a neuron's dendritic spine, the location of CaMKII is controlled by a number of interacting facto...
<p><b>A,B </b><i>In situ</i> hybridization for CaMKIIα mRNA. <b>A,</b> On a horizontal section, CaMK...
uni-muenchen.de It is widely believed that activity-dependent synaptic plasticity is the basis for l...
In a neuron's dendritic spine, the location of CaMKII is controlled by a number of interacting facto...
Activity-dependent and synapse-specific translation of mRNAs is required for long-term changes in sy...
Synaptic transmission in neurons is a measure of communication at synapses, the points of contact be...
CPEB is a sequence-specific RNA binding protein that regulates translation at synapses. In neurons o...
In neurons, the proteins derived from mRNAs localized in dendrites have been implicated in synaptic ...
Regulation of mRNA localization is a conserved cellular process observed in many types of cells and ...