Using Mice to Treat (Wo)men: Mining Genetic Changes in Patient Xenografts to Attack Breast Cancer
- Oesterreich, Steffi
- Brufsky, Adam M.
- Davidson, Nancy E.
Publication date
September 2013
DOI Publisher
The Authors. Published by Elsevier Inc.Abstract
In this issue of Cell Reports, Li et al. show that the analysis of genetic changes in patient-derived xenografts can reveal crucial details of tumor evolution, such as the emergence of functional estrogen receptor mutations in endocrine-resistant breast cancer
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