AbstractWe investigate the existence of relative (m, 2, k, λ)-difference sets in a group H × N relative to N. One can think of these as ‘liftings’ or ‘extensions’ of (m, k, 2λ)-difference sets. We have to distinguish between the difference sets and their complements. In particular, we prove: •— Difference sets with the parameters of the classical Singer difference sets describing PG(d, q) never admit liftings to relative difference sets with n = 2.•— Difference sets of McFarland and Spence type cannot be extended to relative difference sets with n = 2 (with possibly a few exceptions).•— Paley difference sets are not liftable.•— Twin prime power difference sets and their complements never lift.•— Menon...