AbstractSREBPs are transcriptional activators central to cholesterol homeostasis. Recent work has shown that a two-step cleavage of membrane-bound SREBPs frees them to enter the nucleus. An activator of the first, sterol-regulated proteolysis step has also been identified
Sterol regulatory element-binding protein (SREBP) transcription factors regulate cellular lipogenesi...
openSterol regulatory element binding proteins (SREBPs) are a family of transcription factors that r...
Feedback regulation of cholesterol biosynthesis is mediated by membrane-bound transcription factors ...
AbstractSREBPs are transcriptional activators central to cholesterol homeostasis. Recent work has sh...
Presents Cholesterol homeostasis in mammalian cells is regulated at the level of transcription throu...
AbstractTranscriptional regulation and membrane traffic have traditionally been quite separate field...
AbstractCholesterol homeostasis in animal cells is achieved by regulated cleavage of membrane-bound ...
SummaryThis paper describes a convergent mechanism for the feedback control of cholesterol synthesis...
ate cholesterol synthesis and uptake. This system maintains cholesterol homeostasis by increasing ch...
SREBP complex is incorporated into COPII-coated vesicles that bud from the ER and carry the SREBPs t...
AbstractThree new studies have wide implications for cholesterol homeostasis, identifying a novel me...
AbstractSterol regulatory element binding proteins (SREBPs) are transcription factors attached to th...
SummaryThe sterol regulatory element binding protein (SREBP) family of transcription factors control...
The regulatory pool of cholesterol is located in the endoplasmic reticulum (ER) and is key to how ma...
Sterol regulatory element binding proteins (SREBPs) are a family of transcription factors that regul...
Sterol regulatory element-binding protein (SREBP) transcription factors regulate cellular lipogenesi...
openSterol regulatory element binding proteins (SREBPs) are a family of transcription factors that r...
Feedback regulation of cholesterol biosynthesis is mediated by membrane-bound transcription factors ...
AbstractSREBPs are transcriptional activators central to cholesterol homeostasis. Recent work has sh...
Presents Cholesterol homeostasis in mammalian cells is regulated at the level of transcription throu...
AbstractTranscriptional regulation and membrane traffic have traditionally been quite separate field...
AbstractCholesterol homeostasis in animal cells is achieved by regulated cleavage of membrane-bound ...
SummaryThis paper describes a convergent mechanism for the feedback control of cholesterol synthesis...
ate cholesterol synthesis and uptake. This system maintains cholesterol homeostasis by increasing ch...
SREBP complex is incorporated into COPII-coated vesicles that bud from the ER and carry the SREBPs t...
AbstractThree new studies have wide implications for cholesterol homeostasis, identifying a novel me...
AbstractSterol regulatory element binding proteins (SREBPs) are transcription factors attached to th...
SummaryThe sterol regulatory element binding protein (SREBP) family of transcription factors control...
The regulatory pool of cholesterol is located in the endoplasmic reticulum (ER) and is key to how ma...
Sterol regulatory element binding proteins (SREBPs) are a family of transcription factors that regul...
Sterol regulatory element-binding protein (SREBP) transcription factors regulate cellular lipogenesi...
openSterol regulatory element binding proteins (SREBPs) are a family of transcription factors that r...
Feedback regulation of cholesterol biosynthesis is mediated by membrane-bound transcription factors ...
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